Urosepsis due to Multi Drug Resistant Myroides odoratimimus: A Case Report

Abstract

A 41 year old male; a known case of frontal astrocytoma was brought to this centre with history of headache, altered sensorium and an episode of seizure. He was diagnosed as a case of anaplastic astrocytoma six months back and underwent surgical resection followed by chemotherapy and radiotherapy. Clinical evaluation revealed bedridden but responsive patient with Glasgow coma scale of 6/15. Radiological investigations confirmed recurrence of lesion in right frontal lobe. He was admitted to the intensive care unit (ICU) and underwent emergent surgical resection of the tumor.The patient had a stormy post-operative course, requiring ventilatory as well as ionotropic support. Histopathological examination of the resected tumor specimen confirmed a grade III anaplastic astrocytoma. On third post-operative day, he developed continuous, moderate to high grade fever with features of hemodynamic instability. Total leucocytes count increased from 11500/cumm on first post-operative day to 16,200/cumm. Peripheral blood smear examination indicated neutrophilia with left shift and toxic granulation. Urine examination showed presence of traces of albumin, reducing substances and numerous pus cells. Blood, urine and surgical drain samples were sent to microbiology laboratory for culture and antibiotic sensitivity testing. International Journal of Current Microbiology and Applied Sciences

Myroides odoratimimus urinary tract infection in an immunocompromised patient: an emerging multidrug-resistant micro-organism

“…In literature there are several cases which associate Myroides spp. with different types of infections such as soft tissue infections [ 6 , 19 ], UTI [ 16 – 18 ], sepsis [ 2 , 20 ], bacteremia [ 21 , 22 ], cellulitis [ 23 , 24 ], pericardial effusion [ 25 ], pediatric severe burn injury [ 26 ], fulminant erysipelas [ 27 ] and urosepsis [ 28 ]. Many of these case reports were from India, Turkey, Syria Tunisia, Belgium, Italy and Greece.…”

<i>Myroides odoratimimus</i>: a New Threat with Persistent Infections, Multidrug Resistance, and the Potential for Hospital Outbreaks

“…In infections caused by Myroides species, which mainly affect the urinary tract, the urinary tract can be a source of systemic spread. For example, M. odoratimimus has been reported to be isolated in both urine and blood culture of a patient with anaplastic astrocytoma from India (30).…”

Extensively drug-resistant <em>Myroides odoratimimus</em> &ndash;&nbsp;a case series of urinary tract infections in immunocompromised patients

“…A recently published Indian case report discussed isolating M. odoratimimus from both urine and blood cultures of a patient with anaplastic astrocytoma. 28 …”