Urinary Tract Infections in Surgical Patients

Ramanathan, Rajesh; Duane, Therèse M.

doi:10.1016/j.suc.2014.08.007

Cited by 30 publications

(30 citation statements)

References 62 publications

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“…Current guidelines highlight that the diagnosis of symptomatic urinary tract infection requires the presence of clinical symptoms as well as positive urine culture [30,31]. However, Fig.…”

Section: Discussionmentioning

confidence: 99%

Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria

Iftimie

García-Heredia

Pujol

et al. 2016

Eur J Clin Microbiol Infect Dis

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Urinary tract infections (UTI) are common among elderly patients in residential care facilities, as well as in the hospital setting. Identifying new biochemical markers of UTI is an active line of research since UTI management is resource intensive. Paraoxonase-1 (PON1) forms part of the patient's immune system, the response-to-injury and inflammation. Our study sought to evaluate alterations in inflammation-related paraoxonase-1 (PON1) and chemokine (C-C motif) ligand 2 (CCL2) in patients with an indwelling catheter to assess their potential usefulness as biomarkers of infection. Patients (n = 142) who had had the urinary catheter removed and 100 healthy volunteers were recruited. In all participants we measured serum PON1 activity, PON1 concentration, CCL2, procalcitonin and C-reactive protein (CRP). Results indicated that patients had higher CCL2, CRP and procalcitonin concentrations than the control group, and lower paraoxonase activity. There were no significant differences in PON1 concentrations. When comparing the diagnostic accuracy of CRP, procalcitonin, CCL2 and the PON1-related variables in discriminating between patients with and those without UTI, we found a considerable degree of overlap between groups, i.e., a low diagnostic accuracy. However, there were significant inverse logarithmic correlations between serum paraoxonase activity and the number of days the urinary catheter had been in situ. Our results suggest that measurement of these biochemical variables may be useful in investigating complications of long-term use of these devices and help to improve the economic and clinical investment required in the management of the often-associated infection.

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“…Current guidelines highlight that the diagnosis of symptomatic urinary tract infection requires the presence of clinical symptoms as well as positive urine culture [30,31]. However, Fig.…”

Section: Discussionmentioning

confidence: 99%

Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria

Iftimie

García-Heredia

Pujol

et al. 2016

Eur J Clin Microbiol Infect Dis

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“…UTIs are also an underestimated cause of post‐operative morbidity and mortality. The rates of post‐operative UTI range from 1.8% to 4.1% and are associated with increased length of hospitalization, increased prosthetic infections and indeed increased mortality . The majority of these UTIs are due to indwelling catheters and are the most common healthcare‐acquired infection that is generally preventable .…”

Section: Discussionmentioning

confidence: 99%

“…The majority of these UTIs are due to indwelling catheters and are the most common healthcare‐acquired infection that is generally preventable . Of those patients who develop UTI, about 25% will become symptomatic and 1–4% will develop urosepsis . Apart from appropriate insertion techniques, the most important preventative measure to decrease the incidence of UTI is strict criteria for insertion, early removal of the catheter and improved care of the catheter and urine collection bag.…”

Section: Discussionmentioning

confidence: 99%

Quality improvement in surgery: introduction of the American College of Surgeons National Surgical Quality Improvement Program into New South Wales

Richardson

Cox

Shakeshaft

et al. 2019

ANZ Journal of Surgery

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Background: Quality improvement in surgery requires accurate, reliable, risk-adjusted and comparative data. The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) takes reliable clinical data and provides risk-adjusted comparisons with more than 800 hospitals. This paper describes the early outcomes of introducing this programme into New South Wales (NSW). Methods: Four NSW hospitals formed a collaborative. Surgical clinical reviewers were trained and data collected. Risk-adjusted reports were returned to individual hospitals and the NSW Collaborative. Results: The results identified that the NSW Collaborative were outliers for the following causes of morbidity: urinary tract infections, surgical site infections, pneumonia and 30-day readmissions. Conclusion: We have shown that ACS-NSQIP can be adapted to Australia and there is a plan to widen the programme in NSW.

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“…It is estimated that 50% of patients with short-term Foley catheters (up to 7 days) get CAUTI. (21,22) Biofilm formation in Foley catheters is a process that depends on a series of physical and chemical factors, such as the presence of nutrients and urinary flow, design and length of exposure to the device. (23) Researchers have shown that Foley catheter exposure time for biofilm formation varies and depends on the type of microbial consortia and material.…”

Section: Discussionmentioning

confidence: 99%

Cateter urinário: o tempo de exposição e calibre podem influenciar na formação de biofilme?

et al. 2018

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535 30 YEARS 30 YEARS 1 9 8 8 -2 0 1 8 Acta Paul Enferm. 2018; 31(5):535-41.Urinary catheter: can exposure time and gauge affect biofi lm formation?Cateter urinário: o tempo de exposição e calibre podem infl uenciar na formação de biofi lme? Catéter urinario: ¿el tiempo de exposición y calibre puede infl uir en la formación de biofi lm? AbstractObjective: To assess the effects of expos ure time and gauge of Foley catheters in biofi lm formation. Method: In vitro study with samples of Foley catheter fragments made of siliconized latex of different gauges (#14 and #16 French gauge). Artifi cial urine was produced, which was inoculated with Staphylococcus aureus (ATCC 25923) and Pseudomonas aeruginosa (ATCC 27853) standard bacteria, incubated at 37 °C for 24 hours and 72 hours. The material was analyzed by means of culture (bacterial load) and scanning electron microscopy. Results: There was no difference in bacterial load of biofi lms formed in Foley catheter surfaces with regard to different gauges (p > 0.05). On the other hand, exposure time (24 hours and 72 hours) was a determining factor for P. aeruginosa biofi lm formation in Foley catheters (p < 0.05). Conclusion: Exposure time had an effect on P. aeruginosa biofi lm formation in Foley catheters, regardless of gauges. ResumoObjetivo: Avaliar a infl uência do tempo de exposição e calibre na formação de biofi lme em cateteres urinários de Foley (CUFs). Método: Pesquisa in vitro com amostras de fragmentos de CUFs em látex siliconizado de diferentes calibres (n° 14 e n° 16 Frenchs). A urina artifi cial foi confeccionada, inoculada com bactérias-padrão Staphylococcus aureus (ATCC 25923) e Pseudomonas aeruginosa (ATCC 27853) e incubada a 37 °C por 24 horas e 72 horas. As análises foram realizadas por meio de cultura (carga bacteriana) e microscopia eletrônica de varredura. Resultados: Não houve diferença na carga bacteriana dos biofi lmes formados nas superfícies dos CUFs com relação aos diferentes calibres (p > 0,05). Por outro lado, o tempo de exposição (24 horas e 72 horas) foi o fator determinante para formação do biofi lme de P. aeruginosa nos CUFs (p < 0,05). Conclusão: O tempo de exposição infl uenciou a formação do biofi lme de P. aeruginosa nos CUFs, independentemente dos calibres. ResumenObjetivo: Evaluar la infl uencia del tiempo de exposición y calibre en la formación de biofi lm en catéteres urinarios de Foley (CUFs). Método: Investigación in vitro con muestras de fragmentos de CUFs en látex siliconizado de diferentes calibres (n ° 14 y nº 16 Frenchs). La orina artifi cial fue confeccionada, inoculada con bacterias estándar Staphylococcus aureus (ATCC 25923) y Pseudomonas aeruginosa (ATCC 27853) e incubada a 37 °C durante 24 horas y 72 horas. Los análisis se realizaron por medio de cultivo (carga bacteriana) y microscopía electrónica de exploración. Resultados: No hubo diferencia en la carga bacteriana de los biofi lmes formados en las superfi cies de los CUFs en relación con los diferentes calibres (p> 0,05). Por otro lado, el tiempo de exposición (24...

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Urinary Tract Infections in Surgical Patients

Cited by 30 publications

References 62 publications

Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria

Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria

Quality improvement in surgery: introduction of the American College of Surgeons National Surgical Quality Improvement Program into New South Wales

Cateter urinário: o tempo de exposição e calibre podem influenciar na formação de biofilme?

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