Urinary tract infections in neonates with jaundice in their first two weeks of life

Abstract

UTI should be investigated in neonates with hyperbilirubinemia of unknown etiology in the first two weeks of life.

Urinary tract infections in neonates with unexplained pathological indirect hyperbilirubinemia: Prevalence and significance

“…UTIs are well-known to cause prolonged jaundice and are investigated routinely. On the other hand, some authors suggest investigating UTI also in the neonates requiring treatment for pathologic indirect hyperbilirubinaemia, 3,4,6,7,9 while some do not. 5,8 Therefore, it is controversial to look for UTI in these patients.…”

“…4,11 Two other studies from Turkey examined UTI prevalence in <2-week-old newborns with asymptomatic, unexplained indirect hyperbilirubinemia. 6,9 Bilgen et al 6 examined 102 patients and reported UTI as 8%. Most recently, Mutlu et al 9 studied 104 patients and reported UTI as 18%.…”

“…6,9 Bilgen et al 6 examined 102 patients and reported UTI as 8%. Most recently, Mutlu et al 9 studied 104 patients and reported UTI as 18%. The first study was reported from a more developed city (Istanbul) 6 than the later one (Erzurum).…”

“…It is still controversial to test for UTI in patients with unexplained jaundice presenting in the first 2 weeks of life. 3e9 Hence, some authors suggest investigating these neonates requiring treatment for pathologic indirect hyperbilirubinemia for UTIs, 3,4,6,7,9 while some do not. 5,8 In this report, we aimed to study the prevalence and significance of UTIs in neonates presenting with indirect hyperbilirubinemia in the first 2 weeks of life requiring phototherapy who were found to have no other abnormality in their aetiologic workup.…”

Urinary Tract Infections in the Infant

“…35–38 Onset of jaundice after 8 days of life in particular has been associated with UTI. 37,39 Twenty-eight of 30 infants with UTI-induced jaundice had indirect hyperbilirubinemia, and about half of them had renal cortical changes on DMSA scan.…”