Urinary excretion of oxalic acid in chronic renal failure and after kidney transplantation

Influence of Water and Sodium Diuresis and Furosemide on Urinary Excretion of Vitamin B₆, Oxalic Acid and Vitamin C in Chronic Renal Failure

“…In the present study we found that urinary excretion of vitamin B 6 depends on urinary water excretion as does the excretion We could not establish from the results of our previous studies whether urinary excretion of vitamin B 6 is a pro-of oxalic or ascorbic acid [5,6]. This fact was also confirmed by the findings that urinary excretion of vitamin cess which is dependent on sodium or water excretion, although there was a supposition that urinary excretion B 6 , oxalic acid and vitamin C did not increase in CRF patients using the diet with restriction of proteins (35 g/ repeated administration of large doses of furosemide to CRF patients may lead to decreased tubular reabsoption day) and with increased intake of sodium chloride (15 g/ day). The increase of urinary excretions of vitamin B 6 , of oxalic acid and consequently to the decrease in oxalaemia.…”

“…a deficiency of vitamin B 6 and vitamin C. This negative side effect of furosemide can be potentiated in vitamin C depend on water excretion [6]. Furosemide is a diuretic which influences renal tubular transport of patients during renal replacement therapy by losses of vitamin B 6 and C into the dialysis fluid especially using electrolytes.…”

“…administration of furosemide in CRF men. The investigation was performed with restriction of sodium patients led to a significant increase of urinary excretion chloride in the diet (2 g/day) or with high sodium chloride intake of vitamin B 6 . During sodium diuresis, urinary excretion Urinary excretion of oxalic acid and vitamin C signifiexcretion of sodium, vitamin B 6 , oxalic acid and vitamin C were investigated in another group of 15 CRF patients.…”

“…excretion of vitamin B 6 , oxalic acid and vitamin C sig-Glyoxalate is formed from glycine and glycolate [3,4]. nificantly increased during maximal water diuresis Vitamin B 6 catalyzes transformation of glyoxalate to glywhile during high intake of sodium chloride the urinary cine. This is saving metabolic way against oxalate formaexcretions of these substances were not affected.…”

“…Oxalic acid is a uremic toxin and secondary results suggest that urinary excretion of vitamin B 6 , hyperoxalaemia is one of the constant signs of uremic oxalic acid and vitamin C depends on the urinary excre-syndrome in chronic renal failure. In spite of much data in literature about the clinical semide led to an increase of urinary excretion of vitamin importance of vitamin B 6 , oxalic acid and vitamin C in B 6 , oxalic acid and vitamin C in patients with chronic chronic renal failure, there is only little or no data about renal failure. The increased urinary excretion of vitamin the urinary excretion of these substances during maximal Urinary vitamin B 6 was determined by radioenzymatic assay using water diuresis and sodium diuresis [5,6] and after i.v.…”