Urinary calcium to creatinin ratio in children

Abstract

Due to difficulty of 24hr urine collection in children for detection of hypercalciura, random urine calcium to creatinin ratio (U Ca/Cr) has been used for screening hypercalciuria. The purpose of this study was to determine normal U Ca/Cr ratio in primary school age children in North of Iran. This study was performed on 590 healthy school-age children, aged between 7-11 years. Early morning random urine samples from all children were analyzed for calcium and creatinine. Mean value and 95th percentile for U Ca/Cr ratio were 0.155 +/- 0.095 and 0.36, respectively. A negative correlation observed between age and U Ca/Cr ratio was R=-0.101, P=0.014. With regard to variations in U Ca/Cr ratio among different studies, it is recommended to determine this ratio in every geographic area.

Determination of upper reference value of urinary calcium-creatinine ratio for the paediatric population in Burdwan district

“…So the present study was conducted to establish a reference interval in our study area and it was first found that there was a significant inverse relationship between urinary Ca/Cr ratio and age. This finding was well corroborated with several previous studies [9,16,[19][20][21][22]. It also observed that for every age group, different urine Ca/Cr ratio was reported [3,8,23].…”

“…As for most analytes, the lower and upper reference limits are assumed to demarcate the estimated 2.5 th and 97.5 th percentiles respectively, of the underlying distribution of values [24], percentile values of urinary Ca/Cr ratio were calculated. 95 th and 97.5 th percentile for urinary Ca/Cr ratio of different age groups in present study in this geographic area was the same as some reports and different with other [1,6,9,10,[14][15][18][19][20][21][22][23][25][26][27][28][29]. Then upper reference value of urinary Ca/Cr ratio of different age group were found and this to some extent different from one previous study [11].…”

“…It is may be secondary to low creatinine excretion per unit body mass [8] and also tubular immaturity to excrete creatinine [11]. If sex factor is considered, as previous reports it was found that there was no significant difference in urinary Ca/Cr ratio between both sex [9,13,19,22]. As for most analytes, the lower and upper reference limits are assumed to demarcate the estimated 2.5 th and 97.5 th percentiles respectively, of the underlying distribution of values [24], percentile values of urinary Ca/Cr ratio were calculated.…”

Infrared spectroscopic analysis of urinary stones (including stones induced by melamine-contaminated milk powder) in 189 Chinese children

“…In Chinese children, the predominantly vegetarian diet containing higher oxalate and lower calcium may be the reason for the relatively high rate of whewellite stones, especially in older children with eating habits more similar to adults' than younger children. Weddellite stones are related to high urinary excretion of calcium, which decreases with age in children [11,12]. Thus, weddellite stones occurred more often in younger children.…”

Urolithiasis in Childhood: Review

“…Hiperkalsiüri ve taş olgularında aile öyküsünde %40 oranında ürolitiyaz öyküsü vardır. 31,[81][82][83][84] İyi bir diyet öyküsü alınmalıdır. Hastanın sıvı ve tuz tü-ketimi, C vitamini veya D vitamini desteği, özel diyet (ketojenik diyet gibi) alıp almadığı sorgulanmalıdır.…”