2007
DOI: 10.1007/s11926-007-0040-z
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Uric acid nephrolithiasis

Abstract: Uric acid nephrolithiasis is typically found in individuals with a low urine pH and a normal concentration of urinary uric acid. Patients with a history of gout are at greater risk of forming uric acid stones, as are patients with obesity, diabetes, or the complete metabolic syndrome. The unifying renal tubular abnormality of these disorders appears to be the excretion of abnormally acidic urine. This article focuses on the relationship of these disorders to the development of uric acid stones. The diagnosis o… Show more

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Cited by 57 publications
(44 citation statements)
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“…If the amounts of uric acid are considerable, uric acid or mixed uric acid/COM stones will form. As expected, these types of stones were more prevalent in patients with urinary pH < 5.5 than in those with higher urinary pH (Liebman et al 2007). If the amount of formed uric acid crystals is small, it can be eliminated as asymptomatic crystalluria.…”
Section: Introductionsupporting
confidence: 63%
“…If the amounts of uric acid are considerable, uric acid or mixed uric acid/COM stones will form. As expected, these types of stones were more prevalent in patients with urinary pH < 5.5 than in those with higher urinary pH (Liebman et al 2007). If the amount of formed uric acid crystals is small, it can be eliminated as asymptomatic crystalluria.…”
Section: Introductionsupporting
confidence: 63%
“…1 In general, patients with a history of gout are at greater risk of forming uric acid stones, as are patients with obesity, diabetes, or complete metabolic syndrome. 2 Moreover, elevated serum urate levels are known to lead to gouty arthritis, tophi formation, and uric acid kidney stones. 3 The incidence of uric acid stones varies between countries and accounts for 5% to 40% of all urinary calculi.…”
Section: Introductionmentioning
confidence: 99%
“…These were the main factors why dual-energy CT was not further applied in clinical practice. With the introduction of dual-energy dualsource CT the characterisation of urinary calculi has been demonstrated to be feasible [3,[13][14][15][16][17][18][19].…”
Section: Introductionmentioning
confidence: 99%