Targeted dual-energy single-source CT for characterisation of urinary calculi: experimental and clinical experience

Eiber, Matthias; Holzapfel, Konstantin; Frimberger, M.; Straub, Michael; Schneider, Heike; Rummeny, Ernst J.; Dobritz, Martin; Huber, Armin

doi:10.1007/s00330-011-2231-2

Cited by 56 publications

(31 citation statements)

References 33 publications

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“…Thus, for relatively stationary organs, such as the kidneys, ureter, and bladder, the use of two separate scans to perform dual-energy CT may be feasible. However, even in relatively stationary organs, misregistration can occur, as demonstrated in a recent study that found an average distance between the locations of the same kidney stone in two separate scans of 2.7 mm along the z-axis and 4.3 mm along in the axial plane [27]. …”

Section: Introductionmentioning

confidence: 99%

Feasibility of Discriminating Uric Acid From Non–Uric Acid Renal Stones Using Consecutive Spatially Registered Low- and High-Energy Scans Obtained on a Conventional CT Scanner

Leng

Shiung

et al. 2015

American Journal of Roentgenology

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Objective To demonstrate the feasibility of differentiating uric acid (UA) and non-uric-acid (NUA) renal stones using two consecutive, spatially-registered low- and high-energy scans acquired on a conventional CT system. Materials and Methods A total of 34 patients undergoing clinically indicated dual-source, dual-energy CT exams to differentiate UA and NUA kidney stones were enrolled in this IRB-approved study. Immediately after clinically-indicated dual-source, dual-energy CT and written informed consent, two consecutive scans (one at 80 kV and one at 140 kV) were performed on a conventional CT scanner over the region limited to stones identified on the dual-source scan. After 3D deformable registration of the 80 and 140 kV images, UA and non-UA stones were identified using commercial software. Sensitivity, specificity, and accuracy of stone classification were calculated using the dual-source results as the reference standard. Results A total of 469 stones were identified in dual-source exams (26 UA and 443 NUA). Average in-plane stone diameter was 4.4 ± 2.5 mm (range 2.0 to 18.9 mm). Overall sensitivity, specificity, and accuracy for identifying UA stones were 73%, 90%, and 89%, respectively. The sensitivity, specificity, and accuracy were 95%, 97%, and 97% for stones ≥3 mm (n = 341, 19 UA and 322 NUA). Conclusions Accurate differentiation of UA and NUA renal stones is feasible using two consecutively-acquired and spatially-registered conventional CT scans.

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Section: Introductionmentioning

confidence: 99%

Feasibility of Discriminating Uric Acid From Non–Uric Acid Renal Stones Using Consecutive Spatially Registered Low- and High-Energy Scans Obtained on a Conventional CT Scanner

Leng

Shiung

et al. 2015

American Journal of Roentgenology

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“…This is mainly due to the fact that lung cancer screening protocols to date consist of a low-dose non-contrast enhanced scan and the vast majority of the so far investigated benefits of the DECT technique require contrast material application. Yet, as with the DECT-based urinary calculi characterization one useful non-contrast DECT-approach has found its way into clinical routine [1,5,[44][45][46], in the field of lung nodule characterization, probably, the last word has not been spoken.…”

Section: Dect and Lung Cancer Screeningmentioning

confidence: 96%

Dual-energy snap-shot perfusion CT in suspect pulmonary nodules and masses and for lung cancer staging

Sudarski

Hagelstein

Weis

et al. 2015

European Journal of Radiology

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“…In particular, the temporal resolution of the latest 64-slice spiral CT has improved considerably, making the imaging of coronary arteries clearer and the diagnosis more accurate (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21). In general, study reports have evaluated the diagnostic value of coronary CTA by determining the sensitivity and specificity; however, using these two indicators alone tends to ignore the influence of different interpretations by the observers on the results.…”

Section: Introductionmentioning

confidence: 99%

Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis

Gang

Zhang

et al. 2016

Experimental and Therapeutic Medicine

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Abstract. The aim of the present study was to investigate the effect of heart rate (HR) on the diagnostic accuracy of 256-slice computed tomography angiography (CTA) in the detection of coronary artery stenosis. Coronary imaging was performed using a Philips 256-slice spiral CT, and receiver operating characteristic (ROC) curve analysis was conducted to evaluate the diagnostic value of 256-slice CTA in coronary artery stenosis. The HR of the research subjects in the study was within a certain range (39-107 bpm). One hundred patients suspected of coronary heart disease underwent 256-slice CTA examination. The cases were divided into three groups: Low HR (HR <75 bpm), moderate HR (75≤ HR <90 bpm) and high HR (HR ≥90 bpm). For the three groups, two observers independently assessed the image quality for all coronary segments on a four-point ordinal scale. An image quality of grades 1-3 was considered diagnostic, while grade 4 was non-diagnostic. A total of 97.76% of the images were diagnostic in the low-HR group, 96.86% in the moderate-HR group and 95.80% in the high-HR group. According to the ROC curve analysis, the specificity of CTA in diagnosing coronary artery stenosis was 98.40, 96.00 and 97.60% in the low-, moderate-and high-HR groups, respectively. In conclusion, 256-slice coronary CTA can be used to clearly show the main segments of the coronary artery and to effectively diagnose coronary artery stenosis. Within the range of HRs investigated, HR was found to have no significant effect on the diagnostic accuracy of 256-slice coronary CTA for coronary artery stenosis.

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Targeted dual-energy single-source CT for characterisation of urinary calculi: experimental and clinical experience

Abstract: Targeted dual-energy imaging within one breath-hold is feasible for characterisation of urinary calculi using single-source MDCT allowing minimal anatomical discordance.

Cited by 56 publications

References 33 publications

Feasibility of Discriminating Uric Acid From Non–Uric Acid Renal Stones Using Consecutive Spatially Registered Low- and High-Energy Scans Obtained on a Conventional CT Scanner

Feasibility of Discriminating Uric Acid From Non–Uric Acid Renal Stones Using Consecutive Spatially Registered Low- and High-Energy Scans Obtained on a Conventional CT Scanner

Dual-energy snap-shot perfusion CT in suspect pulmonary nodules and masses and for lung cancer staging

Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis

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