Urethral condylomas in men: experience in 123 patients without previous treatment

Abstract

The most common sexually transmitted infection (STI) is infection by human papillomavirus. There are more than 100 types of human papillomavirus, and over 30 of them involve the genital area. Urethral involvement is uncommon and usually limited to the distal 3 cm of the meatus. There are various treatments for urethral condylomas; as a rule, they are limited by a difficult approach, by recurrences, and by potential complications, the most significant of which is urethral stenosis. The purpose of the treatments is to remove the warts and induce lesion-free periods. Such treatments do not eliminate the infection nor do they prevent continued transmission of the virus. We retrospectively evaluated 123 patients diagnosed and treated for condylomas in the genital area at our Institution between April 2009 and April 2012. The patients' mean age was 28.7 years (range 19-51). Of the 123 patients included, 48 (39%) had a history of previous STIs, most frequently gonococcal urethritis. Three of them had a urethral malformation in the form of hypospadias, and another three reported a previous urologic manipulation (catheterisation). Meatal/urethral condylomas are rare, cryotherapy is simple, easy to apply, and has a very low risk of complications in patients with externally accessible warts.

Seminal human papillomavirus infection and reproduction: a systematic review and meta‐analysis

“…HPV infection in men has been considered to be transient, 5 with a main clinical expression being warts in the external genitals. However, the presence of HPV has also been documented in the testicles, epididymis, vas deferens, prostate, urethra, and semen 5–8 …”

Misdiagnosis of Primary Urethral Condyloma Acuminata with Papillary Cancer: a Case Report

“…Surgical excision, cryotherapy, laser therapy, and electrocautery are also appropriate treatment options (18). Such treatments do not eliminate the infection nor do they prevent continued transmission of the virus (19). Our patient had no condyloma acuminata on the external genitalia and we started treatment with podophyllin; the urethral lesion responds well to this treatment.…”

Ressecção endoscópica de extensa lesão condilomatosa uretral – relato de caso e revisão da literatura

“…Urethral involvement occurs in up to 5% of cases, usually located in the external meatus and limited to 3cm of the most distal part of the urethra. The main complication of this type of lesion in the urethra is bleeding, in rare cases, urinary obstruction 2,9 .…”