“…Several time-series studies were conducted in metropolitan areas to investigate the health effects of air pollution 21,22,23,27,28,31,32,35,36,38,41,42,44,46,49,64,69,74 . Published in 2007, the first studies on the health effects of air pollution in biomass burning areas in the Brazilian Amazon were limited to descriptive studies and focused mainly on asthma 59,61,65,66,72 .…”