Uptrend in mortality from systemic connective tissue diseases: A joinpoint regression analysis among the general population of Brazil, 1996–2016

Rezende, Renata; Vieira, C Sartori; Gismondi, Ronaldo Altenburg; Klumb, Evandro Mendes

doi:10.1016/j.jbspin.2019.03.010

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…Our results are in accordance with those of other studies, which have demonstrated an increasing trend in SLE mortality in Latin America. [23][24][25][26] Recently, Schellinger et al, reported worldwide trends of systemic autoimmune disease mortality from 2001 to 2014. 23 Using the WHO database, the authors showed that the ASMR for SLE in Latin American countries was five times higher than in European countries, a phenomenon not observed in other systemic autoimmune diseases (systemic sclerosis, idiopathic inflammatory myopathies, Sjögren syndrome, mixed connective tissue disease, and ANCA-associated vasculitis) analyzed.…”

Section: Discussionmentioning

confidence: 99%

“…These results confirm the findings of previous studies. [24][25][26] Despite the fact that these studies have some limitations similar to ours, such as using only all-cause mortality without any additional information about disease activity or damage, the data provided is highly relevant. Diverse factors might influence differences in mortality across continents in SLE, mainly genetic and social determinants.…”

Section: Discussionmentioning

confidence: 99%

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Twenty-year trends in all-cause mortality of patients with systemic lupus erythematosus in Mexico: Results from a nationwide health registry

Mendoza‐Pinto

Etchegaray‐Morales

Munguía‐Realpozo

et al. 2022

Lupus

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Objective Regional variations in systemic lupus erythematosus (SLE) mortality may be due to different spectra of local environmental factors. The aim of this study was to assess mortality trends in adults with SLE using a nationwide health registry. Methods Data came from the Dynamic Cubes of the General Direction of Health Information for 1998–2017 for mortality. In patients aged ≥15 years, SLE as the principal cause of death was defined according to ICD-10 code M32 and was classified by sex and age. Joinpoint trend analyses of annual age-standardized mortality rates (ASMR) for SLE patients and non-SLE people were made. Results We identified 11 449 SLE deaths and 9,989,874 non-SLE deaths. The SLE ASMR increased more than the non-SLE ASMR, with a 98.2% cumulative increase in the ratio of SLE to non-SLE deaths. Whereas the non-SLE ASMR remained relatively stable throughout the study period (overall and by sex), the SLE ASMR significantly increased between 1998 and 2009, non-significantly decreased between 2009 and 2013 and non-significantly increased thereafter. Both women and men had a large cumulative increase in the SLE ASMR/non-SLE ASMR ratio (73.9 and 191.3%, respectively). The Southeast region had the largest cumulative increases in the ratio of SLE to non-SLE ASMR (108.8%). Of the 11,449 deaths, 445 (3.8%) were in geographical areas where ≥40% of the population is indigenous. Conclusion SLE mortality rates have increased since 1998 and remain high compared with non-SLE mortality: significant sex and regional disparities persist.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Twenty-year trends in all-cause mortality of patients with systemic lupus erythematosus in Mexico: Results from a nationwide health registry

Mendoza‐Pinto

Etchegaray‐Morales

Munguía‐Realpozo

et al. 2022

Lupus

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“…Limited data are available on the mortality profile related to the spectrum of CTDs. 2 Since there has been an uptrend in overall mortality from CTDs in Brazil, 3 data concerning the characteristics of CTDs are anticipated.…”

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confidence: 99%

Mortality profile related to the spectrum of systemic connective tissue diseases: a retrospective, population-based, case–control study

Vieira

Rezende

Klumb

et al. 2019

Lupus

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Tendencia creciente en la mortalidad por lupus eritematoso sistémico en América Latina como expresión de las desigualdades sociales en salud

Hernández-Negrín

Padilla-Cueto

Morales

2022

Reumatología Clínica

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Uptrend in mortality from systemic connective tissue diseases: A joinpoint regression analysis among the general population of Brazil, 1996–2016

Cited by 4 publications

References 5 publications

Twenty-year trends in all-cause mortality of patients with systemic lupus erythematosus in Mexico: Results from a nationwide health registry

Twenty-year trends in all-cause mortality of patients with systemic lupus erythematosus in Mexico: Results from a nationwide health registry

Mortality profile related to the spectrum of systemic connective tissue diseases: a retrospective, population-based, case–control study

Tendencia creciente en la mortalidad por lupus eritematoso sistémico en América Latina como expresión de las desigualdades sociales en salud

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