Uptake of67Ga-6-mercaptopurines in Morris hepatoma-3924 A

Abstract

67Ga-chloro-6-mercaptopurine and 67Ga-citrato-6-mercaptopurine complexes have been prepared and their distribution in Morris-hepatoma-3924 A-bearing rats studied. The tumour affinity of the gallium-67 compounds varies in the order: 67Ga-chloro-6-mercaptopurine greater than 67Ga-citrato-6-mercaptopurine greater than 67Ga-citrate greater than 67Ga-chloride.

A preliminary study on radiolabeling and quality control of [99mTc]Tc-6-mercaptopurine to develop tumor scintigraphic agent

“…In the past years, 6-MP was radiolabeled with different radionuclides. 6-MP was labeled with [ 14 C]C and [ 35 S]S by Adamson et al [26] and [ 67 Ga]Ga by Guarino et al [27] for different purposes. Hunt et al [28] radiolabeled 6-MP with [ 99m Tc]Tc for cholescintigraphy.…”