Uptake of quercetin reduces larval sensitivity to lambda-cyhalothrin in Helicoverpa armigera

Identification of a novel cytochrome P450 CYP3356A1 linked with insecticide detoxification in Bradysia odoriphaga

“…In our previous study, we reported the median lethal concentration (LC 50 ) of the susceptible B. odoriphaga population to imidacloprid (4.08 mg L −1 ; 95% CI 3.92–4.26 mg L −1 ), thiamethoxam (10.91 mg L −1 ; 9.92–12.05 mg L −1 ), chlorpyrifos (17.00 mg L −1 ; 16.29–17.74 mg L −1 ) and β‐cypermethrin (24.37 mg L −1 ; 22.84–26.04 mg L −1 ) . As a synergist, piperonyl butoxide (PBO) can inhibit the activity of cytochrome P450 in insects, therefore, the insecticide toxicity of imidacloprid, thiamethoxam, chlorpyrifos and β‐cypermethrin after PBO treatment was evaluated in this study. Briefly, PBO was dissolved in acetone at a concentration of 150 mg L −1 , and then newly emerged fourth‐instar larvae of B. odoriphaga were dipped into the PBO solution for 15 s. After 2 h, the toxicity of imidacloprid, thiamethoxam, β‐cypermethrin and chlorpyrifos to PBO‐treated B. odoriphaga larvae was evaluated using a standard contact and stomach bioassay method .…”

“…Besides regulating the titers of endogenous compounds such as hormones, fatty acids and steroids, this enzyme system is also well known for its roles in the oxidative metabolism of xenobiotics such as insecticides and plant allelochemicals in pest insects . More importantly, transcriptional overexpression of P450 genes and the corresponding enhanced metabolic ability are often found in insecticide‐resistant populations, and this appears to be a common phenomenon in the evolution of resistance . For example, overexpression of CYP4Q3 contributes to imidacloprid resistance in a Colorado potato beetle Leptinotarsa decemlineata resistant strain, and overexpression of cytochrome P450 CYP6CM1 is linked to high resistance to imidacloprid in the B and Q biotypes of Bemisia tabaci (Hemiptera: Aleyrodidae) .…”

“…[5][6][7][8] More importantly, transcriptional overexpression of P450 genes and the corresponding enhanced metabolic ability are often found in insecticide-resistant populations, and this appears to be a common phenomenon in the evolution of resistance. [9][10][11][12] For example, overexpression of CYP4Q3 contributes to imidacloprid resistance in a Colorado potato beetle Leptinotarsa decemlineata resistant strain, 13 and overexpression of cytochrome P450 CYP6CM1 is linked to high resistance to imidacloprid in the B and Q biotypes of Bemisia tabaci (Hemiptera: Aleyrodidae). 14 Expression of CYP9M10 was 260-fold higher in a permethrin-resistant Culex quinquefasciatus strain, compared with the susceptible strain.…”

Exposure to herbicides reduces larval sensitivity to insecticides in Spodoptera litura (Lepidoptera: Noctuidae)

“…Remarkably, B. odoriphaga larvae reared on garlic and humus were less susceptible to phoxim and clothianidin . Likewise, reduced λ-cyhalothrin susceptibility was observed for quercetin-fed H. armigera larvae, suggesting that quercetin (a plant flavonol) may compromise the efficacy of pyrethroid insecticides (Chen et al, 2018). Furthermore, CarE activity in silverleaf whitefly (B. tabaci) adults from subpopulations reared on cabbage and cucumber were significantly increased as compared to other host plants.…”

Phenotypic and Transcriptomic Response of the Grasshopper Oedaleus asiaticus (Orthoptera: Acrididae) to Toxic Rutin

“…Rutin, a widely distributed flavonoid glycoside, generally can help plants resist insect attack (Chen et al, 2017). The extracted flavonoid rutin from plants has deleterious effects on the pest insects Lymantria dispar, Spodoptera litura, Pectinophora gossypiella, Heliothis virescens, Spodoptera eridania, and Helicoverpa zea (Simmonds, 2003;Salunke et al, 2005;Mesbah et al, 2007;Taggar and Gill, 2016).…”