Uptake and controlled release of a dye from thermo-sensitive polymer P(NIPAM-co-Vim)

Śliwa, Tomasz; Jarzębski, Maciej; Andrzejewska, Ewa; Szafran, M.; Gapiński, Jacek

doi:10.1016/j.reactfunctpolym.2017.04.003

Cited by 22 publications

(8 citation statements)

References 38 publications

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“…Accompanied with the variation, the phase separation will happen, and polymer will cement out or dissolve in the solvent. Because of this special property, the application thermo‐sensitive copolymers have been studied extensively . Recently, researchers have developed their study to design and copolymerize thermo‐sensitive with other functional monomers to prepare a special material for special use.…”

Section: Introductionmentioning

confidence: 99%

“…Because of this special property, the application thermo-sensitive copolymers have been studied extensively. [28][29][30] Recently, researchers have developed their study to design and copolymerize thermo-sensitive with other functional monomers to prepare a special material for special use. The study about copolymerization could be separated to random copolymerization, 31,32 graft copolymerization, 33,34 block copolymerization, 35,36 and their combinations.…”

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confidence: 99%

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Design and synthesis study of the thermo‐sensitive copolymer carrier of penicillin G acylase

Chen

Liu

et al. 2018

Polymers for Advanced Techs

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Reversible‐addition‐fragmentation chain transfer polymerization method was adopted here in this study to prepare a series of thermo‐sensitive tri‐block copolymer carrier, poly(N,N‐diethylacrylamide‐b‐β‐hydroxyethyl methacrylate‐b‐glycidyl methacrylate), PDEA‐b‐PHEMA‐b‐PGMA (named as DHG). Their structures and temperature sensitivity performances were further characterized by the nuclear magnetic resonance, the gel permeation chromatography, and the fluorescence spectroscopy, respectively. It has been identified that the synthesis reaction of tri‐block copolymer was living polymerization. The thermo‐sensitivity study suggested that 2 monomers, β‐hydroxyethyl methacrylate and glycidyl methacrylate, played key roles on the lower critical solution temperature performance. Finally, above block copolymer was conscripted to immobilize penicillin G acylase; relationships among the number‐average molar weight ()trueM¯n of the 2 monomer, β‐hydroxyethyl methacrylate and glycidyl methacrylate, loading (L), and activity recover rate (Ar) of immobilized PGA were investigated. And the results showed that L and Ar arrived at 19 502 U and 92%, respectively.

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Section: Introductionmentioning

confidence: 99%

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confidence: 99%

Design and synthesis study of the thermo‐sensitive copolymer carrier of penicillin G acylase

Chen

Liu

et al. 2018

Polymers for Advanced Techs

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“…A phthalate‐imprinted thermosensitive polymer SPME fiber was prepared in accordance with the polymerization method reported in previous studies . Details of the preparation of the optical fiber coated with a temperature‐sensitive polymer are mentioned in Section .…”

Section: Resultsmentioning

confidence: 99%

Coating of optical fiber with a smart thermosensitive polymer for the separation of phthalate esters by solid‐phase microextraction

Hashemi‐Moghaddam

Maddah

2017

J of Separation Science

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A solid‐phase microextraction fiber was prepared by coating an optical fiber with a temperature‐sensitive polymer to determine phthalate esters. N‐Isopropylacrylamide and N,N′‐methylenebisacrylamide were used as the monomer and the cross linker, respectively. The fabricated fiber was characterized by FTIR spectroscopy, thermogravimetric analysis, and scanning electron microscopy. During extraction, important factors such as extraction time, pH, temperature, and ionic strength were optimized. The fabricated fiber, which is firm, inexpensive, stable, and efficient, is a vital material used in solid‐phase microextraction. Under optimum conditions, the calibration curve was linear and in the range of 1–20 μg/L (r2 = 0.9747). The high extraction efficiency was obtained for phthalates with a detection limit of 0.12 μg/L. The fabricated fiber was successfully applied to the solid‐phase micro extraction of phthalates from water samples after its extraction, followed by gas chromatography with flame ionization detection.

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“…Due to these properties, nanogels have become an excellent platform in many medical applications, including photo-imaging [ 47 ], tissue regeneration [ 48 ], cancer therapy [ 49 ] and gene delivery [ 50 ]. This is based on their remarkable characteristics, such as their high capacity for drug entrapment and release [ 51 ], tailorable size [ 52 ], tuneable toxicity [ 53 ], high stability, controlled and sustained drug release [ 54 ], precise targeted delivery [ 55 ], and high biodegradability [ 56 ]. Nanogels can be used for drug delivery through oral [ 57 ], pulmonary [ 58 ], nasal [ 59 ], intra-ocular [ 60 ] and topical [ 60 ] pathways.…”

Section: Nanogelsmentioning

confidence: 99%

“…Śliwa et al synthesized a temperature-responsive nanogel with a hydrodynamic diameter of 150–650 nm for the controlled release of orange II. This nanogel was prepared by polymerization of 1-vinylimidazole (Vim) and PNIPAM monomers, with bisacrylamide (BAM) as the crosslinker [ 51 ].…”

Section: Thermosensitive Polymersmentioning

confidence: 99%

Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications

Ghaeini-Hesaroeiye

Bagtash

Boddohi

et al. 2020

Gels

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Nanogels, or nanostructured hydrogels, are one of the most interesting materials in biomedical engineering. Nanogels are widely used in medical applications, such as in cancer therapy, targeted delivery of proteins, genes and DNAs, and scaffolds in tissue regeneration. One salient feature of nanogels is their tunable responsiveness to external stimuli. In this review, thermosensitive nanogels are discussed, with a focus on moieties in their chemical structure which are responsible for thermosensitivity. These thermosensitive moieties can be classified into four groups, namely, polymers bearing amide groups, ether groups, vinyl ether groups and hydrophilic polymers bearing hydrophobic groups. These novel thermoresponsive nanogels provide effective drug delivery systems and tissue regeneration constructs for treating patients in many clinical applications, such as targeted, sustained and controlled release.

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Uptake and controlled release of a dye from thermo-sensitive polymer P(NIPAM-co-Vim)

Cited by 22 publications

References 38 publications

Design and synthesis study of the thermo‐sensitive copolymer carrier of penicillin G acylase

Design and synthesis study of the thermo‐sensitive copolymer carrier of penicillin G acylase

Coating of optical fiber with a smart thermosensitive polymer for the separation of phthalate esters by solid‐phase microextraction

Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications

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