Updates in drug-induced acute pancreatitis

Alhaddad, Omkolsoum; Elsabaawy, Maha; Elfauomy, Marwa; Elsabaawy, Dalia; Mansour, Tarek S.

doi:10.1186/s43066-020-00059-3

Cited by 7 publications

(5 citation statements)

References 34 publications

(41 reference statements)

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“…abdominal ultrasonography, computed tomography, drug-induced acute pancreatitis, fluoroquinolone, levofloxacin, photosensitivity incidence is crossing 50-800 per one million adults. 6 Drug-induced acute pancreatitis can be considered the third common cause of acute pancreatitis after ruling out alcohol and gallstones. 7 Diuretics, valproic acid, and azathioprine are commonly associated with drug-induced acute pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

“…Drug‐induced acute pancreatitis is estimated to account for 5% of all acute pancreatitis cases, and the global incidence is crossing 50–800 per one million adults. 6 Drug‐induced acute pancreatitis can be considered the third common cause of acute pancreatitis after ruling out alcohol and gallstones. 7 Diuretics, valproic acid, and azathioprine are commonly associated with drug‐induced acute pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

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Acute pancreatitis associated with the antibiotic levofloxacin: A rare case report

Inban,

Gulla,

Devani

et al. 2023

Clinical Case Reports

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Key Clinical MessageDrug‐induced acute pancreatitis is a potentially ignored diagnosis that must be precisely valued. Drug‐induced acute pancreatitis can be considered the third common cause of acute pancreatitis after ruling out alcohol and gallstones. Levofloxacin belongs to a class of fluoroquinolone antibiotics used for treating various infections. Besides photosensitivity and liver toxicity, levofloxacin can induce acute pancreatitis, although rarely described. We highlight a case of acute pancreatitis in a female induced by levofloxacin. She presented with typical signs and symptoms of acute pancreatitis and had been taking levofloxacin for urinary tract infections for the last 3 days. After ruling out all other possible causes, her clinical picture, laboratory results, and imaging findings confirmed acute pancreatitis induced by levofloxacin.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Acute pancreatitis associated with the antibiotic levofloxacin: A rare case report

Inban,

Gulla,

Devani

et al. 2023

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

“…Drug-induced acute pancreatitis is estimated to account for 5% of all acute pancreatitis cases, and the global incidence is crossing 50-800 per one million adults [ 6 ]. Drug-induced acute pancreatitis is relatively rare and a diagnosis of exclusion after ruling out alcohol, gallstones, hypertriglyceridemia, and intervention [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Levofloxacin-Induced Acute Pancreatitis: Case Report and Literature Review

Omoregie,

Ugwuoke,

Agho

et al. 2023

Cureus

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Diagnosing acute pancreatitis induced by any drug is often overlooked and warrants careful evaluation. Drug-induced acute pancreatitis is relatively rare, and diagnosis of exclusion after ruling out alcohol, gallstones, hypertriglyceridemia, and intervention. Levofloxacin, a class of fluoroquinolones, is generally recommended against various bacterial infections. While levofloxacin is mainly known for its potential side effects, such as photosensitivity and liver toxicity, it can also rarely induce acute pancreatitis. We report a case of acute pancreatitis in a female patient precipitated by levofloxacin. The patient exhibited typical manifestations of acute pancreatitis and had been taking levofloxacin for a urinary tract infection over the past three days. After ruling out other possible causes, her clinical presentation, laboratory results, and imaging findings confirmed levofloxacin-induced acute pancreatitis.

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“…Severe course has been reported in up to 15% of AIP patients. 13 Other complications can be divided as short-term and long-term AIP complications. Short term complications were defined as pancreatic necrosis and pseudocyst development which mainly occurred during within 4 weeks of acute pancreatitis.…”

Section: Figure 1 Abdominal Ct Scan With Contrast Examination On Four...mentioning

confidence: 99%

Asparaginase-Induced Acute Necrotizing Pancreatitis Resulting in Chronic Pancreatitis and Pseudocyst in an Adult with Acute Lymphocytic Leukemia

Adiwinata

Waleleng

Haroen

et al. 2023

InaJGHE

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L-Asparaginase is one of the main chemotherapy regiments for acute lymphocytic leukemia (ALL) management. Acute pancreatitis is one of the serious side effects of l-asparaginase administration and may lead to interruption of chemotherapy cycle. Long term complications may be devastating for patients which include of pseudocyst pancreas and chronic pancreatitis. Asparaginase induced pancreatitis is rare among adult due to the nature of ALL which commonly occurred in children population. The pathophysiology of asparaginase induced pancreatitis is still unclear. Here we present 18-year-old male with ALL and asparaginase induced acute necrotizing pancreatitis which complicated to chronic pancreatitis and pseudocyst.

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Updates in drug-induced acute pancreatitis

Cited by 7 publications

References 34 publications

Acute pancreatitis associated with the antibiotic levofloxacin: A rare case report

Acute pancreatitis associated with the antibiotic levofloxacin: A rare case report

A Rare Case of Levofloxacin-Induced Acute Pancreatitis: Case Report and Literature Review

Asparaginase-Induced Acute Necrotizing Pancreatitis Resulting in Chronic Pancreatitis and Pseudocyst in an Adult with Acute Lymphocytic Leukemia

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