“…Colorectal cancer, as with all cancer diagnoses, can lead to substantial morbidity or mortality, but whether it is an important enough health problem to screen will require the consideration of the societal impact and epidemiological trends. The large burden of colorectal cancer in East Asia and Oceania, which is largely on par with Europe and North America, supports the implementation of organized CRC screening, 12 but this may not be a straightforward decision for other countries and regions in Southeast Asia and South Asia with varying CRC incidence rates. The natural history of CRC is well understood, and there is a relatively long and recognizable asymptomatic stage.…”
Section: Screening Program Implementationmentioning
“…Colorectal cancer, as with all cancer diagnoses, can lead to substantial morbidity or mortality, but whether it is an important enough health problem to screen will require the consideration of the societal impact and epidemiological trends. The large burden of colorectal cancer in East Asia and Oceania, which is largely on par with Europe and North America, supports the implementation of organized CRC screening, 12 but this may not be a straightforward decision for other countries and regions in Southeast Asia and South Asia with varying CRC incidence rates. The natural history of CRC is well understood, and there is a relatively long and recognizable asymptomatic stage.…”
Section: Screening Program Implementationmentioning
“…Gastrointestinal (GI) cancers, such as gastric cancer and colorectal cancer, remain some of the most prevalent cancers worldwide, resulting in roughly 3.5 million new cases each year. [1][2][3] The early diagnosis of GI cancer and the point-of-care (PoC) monitoring of its prognosis states play a crucial role in improving treatment outcomes. [4][5][6] However, biopsy specimen analysis and imageological examinations, the current techniques for GI cancer diagnosis and prognosis, are either invasive or require specialized instruments or trained personnel, making them impractical for PoC use.…”
Extracellular vesicles (EVs), as a type of subcellular structure, have been extensively researched for their potential in developing advanced diagnostic technologies for various diseases. However, the biomolecular and biophysical heterogeneity...
“…1,2 Especially, in East Asia, gastric cancer has the second highest diagnosis and mortality rate. 3 Surgery, chemotherapy, radiotherapy, and immunotherapy are currently the four main treatment means for gastric cancer in clinics. Although the only radical treatment option for gastric cancer available is still surgical resection, the prognosis of patients with locally advanced gastric cancer (AGC) is severely compromised by the low R0 resection rate.…”
Gastric cancer, a gastrointestinal tumor with high morbidity and lethality, is often treated with operations that are not as effective as they could be due to the locally advanced stage....
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