Update on the management of non-muscle invasive bladder cancer

Aldousari, Saad; Kassouf, Wassim

doi:10.5489/cuaj.777

Cited by 92 publications

(87 citation statements)

References 132 publications

(137 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This result is consistent with the previous studies that have reported positive association between socio-economic factors and life satisfaction. Sacks, Stevenson and Wolfers (2010) and Aldousari and Kassouf (2010) document a positive relationship between subjective wellbeing and education, income and social relationships. Similarly, Frey (2008) found demographic variables like, income, marriage, education and religiousity to be significantly associated with individual happiness.…”

Section: Discussionmentioning

confidence: 99%

The Moderating Effect of Socio-Demographic Characteristics on Subjective Wellbeing

Mayungbo¹

2017

IJSSR

View full text Add to dashboard Cite

The independent association between socio-demographic characteristics and subjective well-being is well studied, however, the moderating impact of those characteristics are yet to be established in literature. This study examines the moderating influence of socio-demographic characteristics on subjective well-being among residents in Ibadan metropolis. Using a descriptive survey design and a multistage sampling technique, 10 enumeration areas each were selected from the five major Local Government Areas (LGAs) with simple random technique. The number of participants on the selected enumeration areas were determined with enumeration area maps. Two hundred and twenty participants each were selected from each LGA, using a systematic technique, making a total of 1,100 participants. A questionnaire focusing on socio-demographic profile and life satisfaction scale (r=0.74) was administered to the participants. Data were analyzed using descriptive statistics, co-relational analysis, moderated hierarchical multiple regression and analysis of variance at 0.05 level of significance. Two hypotheses were tested. The result reveals that socio-demographic factors jointly predicted life satisfaction (F (1, 1007) =4.61, p<.001). Age and marital status also interacted to predict life satisfaction (β=-0.13, t=-3.58, p<.01; β = -0.08, t=1.98, p<.05). The interaction effect of social demographic factors should be considered in a comprehensive examination of subjective wellbeing.

show abstract

Section: Discussionmentioning

confidence: 99%

The Moderating Effect of Socio-Demographic Characteristics on Subjective Wellbeing

Mayungbo¹

2017

IJSSR

View full text Add to dashboard Cite

show abstract

“…Due to its high recurrence rate, bladder cancer has the highest lifetime treatment cost per patient of all cancers [2,3] and requires frequent surveillance. White light cystoscopy (WLC) is the standard imaging tool for detection, resection and surveillance of bladder cancer; however, WLC has well-recognized shortcomings that can adversely impact treatment outcomes.…”

Section: Introductionmentioning

confidence: 99%

Multimodal 3D cancer-mimicking optical phantom

Smith¹,

Lurie²,

Zlatev³

et al. 2016

Biomed. Opt. Express

View full text Add to dashboard Cite

Three-dimensional (3D) organ-mimicking phantoms provide realistic imaging environments for testing various aspects of optical systems, including for evaluating new probe designs, characterizing the diagnostic potential of new technologies, and assessing novel image processing algorithms prior to validation in real tissue. We introduce and characterize the use of a new material, Dragon Skin (Smooth-On Inc.), and fabrication technique, air-brushing, for fabrication of a 3D phantom that mimics the appearance of a real organ under multiple imaging modalities. We demonstrate the utility of the material and technique by fabricating the first 3D, hollow bladder phantom with realistic normal and multi-stage pathology features suitable for endoscopic detection using the gold standard imaging technique, white light cystoscopy (WLC), as well as the complementary imaging modalities of optical coherence tomography and blue light cystoscopy, which are aimed at improving the sensitivity and specificity of WLC to bladder cancer detection. The flexibility of the material and technique used for phantom construction allowed for the representation of a wide range of diseased tissue states, ranging from inflammation (benign) to high-grade cancerous lesions. Such phantoms can serve as important tools for trainee education and evaluation of new endoscopic instrumentation.

show abstract

“…The procedure is performed by preinstilling 5-aminolevulinic acid or hexaminolevulinate in the bladder 30 to 60 minutes before using ultraviolet/blue light cystoscopy. 126 The chemicals are concentrated in the malignant urothelial cells, which are then easily identified with blue light cystoscopy. A meta-analysis using raw data from prospective studies on 1345 patients with known or suspected nonmuscleinvasive bladder cancer compared blue light cystoscopy with white light cystoscopy.…”

Section: Blue-light/fluorescence Cystoscopy Formentioning

confidence: 99%

“…125 Because 50% to 70% of superficial urothelial carcinomas recur, there has been a high demand for better detection techniques. 126 Fluorescence/blue light cystoscopy is a relatively new diagnostic and therapeutic technique that is performed at our institution. In contrast to regular white light cystoscopy where some tumors may be missed because of their small size, blue light cystoscopy, which is an enhanced imaging procedure, helps urologists identify bladder lesions/tumors of any size more easily by using Cysview (hexaminolevulinate hydrochloride, Photocure ASA, Oslo, Norway), which turns malignant cells in the bladder bright pink or red under a blue light (Figure 11, A through F).…”

Section: Blue-light/fluorescence Cystoscopy Formentioning

confidence: 99%

Biomarker, Molecular, and Technologic Advances in Urologic Pathology, Oncology, and Imaging

Ellis

Harik

Cohen

et al. 2017

Archives of Pathology &Amp; Laboratory Medicine

View full text Add to dashboard Cite

Urologic pathology is evolving rapidly. Emerging trends include the expanded diagnostic utility of biomarkers and molecular testing, as well as adapting to the plethora of technical advances occurring in genitourinary oncology, surgical practice, and imaging. We illustrate those trends by highlighting our approach to the diagnostic workup of a few selected disease entities that pathologists may encounter, including newly recognized subtypes of renal cell carcinoma, pheochromocytoma, and prostate cancer, some of which harbor a distinctive chromosomal translocation, gene loss, or mutation. We illustrate applications of immunohistochemistry for differential diagnosis of needle core renal biopsies, intraductal carcinoma of the prostate, and amyloidosis and cite encouraging results from early studies using targeted gene expression panels to predict recurrence after prostate cancer surgery. At our institution, pathologists are working closely with urologic surgeons and interventional radiologists to explore the use of intraoperative frozen sections for margins and nerve sparing during robotic prostatectomy, to pioneer minimally invasive videoscopic inguinal lymphadenectomy, and to refine image-guided needle core biopsies and cryotherapy of prostate cancer as well as blue-light/fluorescence cystoscopy. This collaborative, multidisciplinary approach enhances clinical management and research, and optimizes the care of patients with urologic disorders. (Arch Pathol Lab Med. 2017;141:499-516; doi: 10.5858.arpa.2016-0263-SA) I n this review, we summarize the effect of a number of biomarker, molecular, and technologic advances in urologic pathology, oncology, and imaging on routine, day-to-day practice and research at our institution. The objective of this review is not to cover the entire gamut of all advances that we have and use at our institution but, rather, to highlight a few pertinent concepts in our field. Topics that will be covered include biomarkers, molecular testing of selected malignancies (eg, transcription factor E3 [TFE3]/ Xp11.2 translocation-associated renal cell carcinoma; p63, high-molecular-weight cytokeratin and racemase cocktail [PIN4]/phosphatase and tensin homolog [PTEN] for some cases of intraductal carcinoma of the prostate; and succinate dehydrogenase subunit B in renal cell carcinoma and pheochromocytoma), amyloidosis of the genitourinary tract, and workup of neoplastic needle core kidney biopsies. In addition, we will report the effect of pathologic, oncologic, and radiologic technologic advances (ie, global transcriptome analysis and RNA biomarkers of prostate cancer; robotic-assisted radical prostatectomy; minimally invasive videoscopic inguinal lymphadenectomy; targeted magnetic resonance imaging [MRI]-guided prostate needle core biopsies; anti-1-amino-3-fluorine 18-fluorocyclobutane-1-carboxylic acid in prostate cancer; cryotherapy for prostate cancer; and blue-light/white-light cystoscopy for bladder lesions) performed at our institution.

show abstract

Update on the management of non-muscle invasive bladder cancer

Cited by 92 publications

References 132 publications

The Moderating Effect of Socio-Demographic Characteristics on Subjective Wellbeing

The Moderating Effect of Socio-Demographic Characteristics on Subjective Wellbeing

Multimodal 3D cancer-mimicking optical phantom

Biomarker, Molecular, and Technologic Advances in Urologic Pathology, Oncology, and Imaging

Contact Info

Product

Resources

About