Update on management of polycystic ovarian syndrome for dermatologists

Gainder, Shalini; Sharma, Bharti

doi:10.4103/idoj.idoj_249_17

Cited by 33 publications

(21 citation statements)

References 65 publications

(75 reference statements)

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“…The same results were mentioned by others, who reported PCO in 52-82% of patients with adult acne [ 20 ], and by Borgia et al, who demonstrated PCO in 60 of 129 (46.51%) of patients, but the LH/FSH ratio was increased in only 19 of them, and the ultrasonographic evidence of PCO was not significantly associated with an increased LH/FSH ratio [ 22 ]. Gainder and Sharma demonstrated PCO in half of their patients, but the LH:FSH ratio was increased in a third of them [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

A Comparative Clinical and Laboratory Study of Adolescent and Adult Acne in Iraqi Women

Dhaher¹,

Hamdan²,

Alyasin³

2022

Cureus

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BackgroundAcne vulgaris is a common chronic inflammatory disease of the pilosebaceous units associated with longterm sequelae and complications. Currently, acne in women is classified into adolescent and postadolescent forms. However, comparative studies evaluating the clinical and laboratory parameters across various age groups in women with acne are lacking.The aim of the study is to compare the clinical and laboratory characteristics of different groups of women with acne vulgaris. Patients and methodsOver 3 years (2018-2021), a cross-sectional study was carried out on 340 women with acne consulting the Dermatology and Venereology Outpatient Clinic, Basrah Teaching Hospital, Basrah, Iraq. Eligible patients were carefully evaluated and fully examined, emphasizing on signs of hyperandrogenism and scoring of acne severity. Hormonal assays of serum total testosterone (TST), dehydroepiandrosterone sulfate (DHEAS), luteinizing hormone (LH), follicular stimulating hormone (FSH), and serum prolactin (PRL) were done. Pelvic ultrasonography was performed to identify any pelvic pathology. The patients were classified according to their age of onset. Clinical and laboratory data were compared among groups. ResultsThree groups were recognized: 160 patients (47%) with adolescent acne (AA) (mean age SD: 17.2±1.6 years), 80 (23.5%) with early adult-onset acne (EA) (mean age SD: 21.4±1.2 years), and 100 (29.4%) with postadolescent acne (PA) (mean age SD: 28.7±2.9 years), which were further sub-grouped into late-onset acne (40 cases, 11.7%), and persistent acne (60 cases, 17.6%). The mean body mass index was normal in the AA group and overweight in the EA and PA groups. Moderate obesity was more frequent in PA (24%, p=0.03). While 78.5% of AA was mild to moderate acne, 77.5% of EA was moderate to moderately severe, and 72% of PA was moderately severe to severe. Clinical and biochemical markers of hyperandrogenism were seen in all groups, however, they were more frequent in PA and EA groups than in the AA group (p<005). ConclusionClinical and biochemical hyperandrogenism were present in a significant proportion of women with acne; their prevalence was higher in post-adolescent acne than in adolescent acne. Acne that began between the ages of 20 and 25 was classified as "early adult-onset acne," and showed variable features of hyperandrogenism. A complete evaluation, regardless of age, for every female with acne, including a hormonal analysis and pelvic ultrasound examination to detect hormonal imbalances as early therapy, can help to prevent and reduce the risk of consequences.

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Section: Discussionmentioning

confidence: 99%

A Comparative Clinical and Laboratory Study of Adolescent and Adult Acne in Iraqi Women

Dhaher¹,

Hamdan²,

Alyasin³

2022

Cureus

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“…The complexities attached to PCOS allowed the proposal of three diagnostic criteria in adult women—National Institutes of Health (NIH) in 1990, Rotterdam American Society for Reproductive Medicine and the European Society of Human Reproduction and Embryology (ASRM/ESHRE)-sponsored PCOS Consensus Workshop Group in 2004, and Androgen Excess and PCOS Society (AE-PCOS) in 2006 [ Figure 1 ]. [ 3 ] Lujan et al . [ 4 ] suggested conservative diagnosis due to its characteristics that included appropriate patient education, careful treatment and enduring follow-up of patients as the actual health risks of these distinct phenotypes are slowly revealed.…”

Section: Introductionmentioning

confidence: 99%

A Practitioner’s Toolkit for Polycystic Ovary Syndrome Counselling

Lathia

Joshi

Behl

et al. 2022

Indian Journal of Endocrinology and Metabolism

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Polycystic ovary syndrome (PCOS), a frequently occurring health issue, has a significant effect on the cosmetic, metabolic, psychosocial and fertility aspects of women. A multidisciplinary team approach based on the core pillars of screening, assessment and counselling to detect, prevent and treat physiological and psychological issues in PCOS is very essential. Women are treated medically, but the psychosocial part is often forsaken. Hence, counselling forms an integral part of PCOS management that enables enhanced clinical outcomes and patient satisfaction. Digital tools and PCOS support groups have built an opportunity for physicians to create awareness, help timely diagnosis and overcome PCOS symptoms. The absence of clear guidelines to tackle the often less discussed aspects of PCOS warrants the need for consensus on PCOS counselling. This review summarizes the biopsychosocial health, clinical assessment and treatment strategies of PCOS and associated co-morbidities. The review article will discuss the clinician’s role in patient education with the special focus on counselling of females with PCOS regardless of age group.

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“…[6] Objawy skórne tj. hirsutyzm (50-89% pacjentek z PCOS) , trądzik, łojotok, łysienie, rogowacenie ciemne (5%) [8]. Kobiety z PCOS są bardziej narażone na zaburzenia nastroju, szczególnie depresję oraz zaburzenia lękowe [2].…”

Section: Wprowadzenie I Cel Pracyunclassified

Vitamin D supplementation in Polycystic ovary syndrome

GRZYWNA

Sylwia

Walczak

et al. 2022

J Educ Health Sport

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Introduction and Purpose. Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age worldwide. Patients may present with a wide range of symptoms. According to the most commonly used Rotterdam criteria, the presence of 2 out of 3 criteria is required for diagnosis: clinical and/or biochemical markers of hyperandrogenism (HA); ovulation disorders (oligo- or anovulation); polycystic ovaries on ultrasound (PCOM); and exclusion of disorders mimicking the clinical features of PCOS. The basis of treatment are birth control pills, metformin and antiandrogens. The pathogenesis of the syndrome is not fully understood. The aim of the study is to summarize the potential health benefits of vitamin D supplementation for women with PCOS based on publications from the last 10 years available on Pubmed. State of knowledge. Vitamin D receptors have been identified not only in calcium-regulating tissues, but also in many reproductive organs, such as the ovary (especially granulosa cells), uterus, placenta, testes, as well as hypothalamus and pituitary gland. In recent years, there have been studies analyzing the effect of vitamin D supplementation on the hormonal balance, metabolism and clinical symptoms in women with PCOS. Summary. The results of studies on vitamin D supplementation in women with PCOS are mixed. Some of them are promising and confirm a beneficial effect on glucose metabolism and insulin resistance, lipid metabolism, hormonal balance, alleviation of HA-related symptoms, improvement of menstrual frequency; while the results of other studies do not show significant improvement and do not confirm these effects. Therefore, there is a need for further research on the relationship between the pathogenesis of PCOS and vitamin D and the impact of its supplementation.

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Update on management of polycystic ovarian syndrome for dermatologists

Cited by 33 publications

References 65 publications

A Comparative Clinical and Laboratory Study of Adolescent and Adult Acne in Iraqi Women

A Comparative Clinical and Laboratory Study of Adolescent and Adult Acne in Iraqi Women

A Practitioner’s Toolkit for Polycystic Ovary Syndrome Counselling

Vitamin D supplementation in Polycystic ovary syndrome

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