Update on local allergic rhinitis

Altıntoprak, Niyazi; Kar, Murat; Muluk, Nuray Bayar; Öktemer, Tuğba; Ipci, Kagan; Birdane, Leman; Arıcıgil, Mitat; Şentürk, Mehmet Baki; Bafaqeeh, Sameer Ali; Cingi, Cemal

doi:10.1016/j.ijporl.2016.06.008

Cited by 21 publications

(22 citation statements)

References 55 publications

(75 reference statements)

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“…This leads to a question whether good response to intranasal corticosteroids could differentiate LAR from AR. Similar to AR, topical nasal steroids and oral antihistamine is the recommended treatment of LAR (34) . AR generally responds well to intranasal corticosteroids, however studies on its benefit in NAR had been variable.…”

Section: Subgroup Analysismentioning

confidence: 99%

Local specific Immunoglobulin E among patients with nonallergic rhinitis: a systematic review

Hamizan¹,

Rimmer²,

Husain³

et al. 2018

Rhin

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Section: Subgroup Analysismentioning

confidence: 99%

Local specific Immunoglobulin E among patients with nonallergic rhinitis: a systematic review

Hamizan¹,

Rimmer²,

Husain³

et al. 2018

Rhin

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“…Several authors suggested that allergic/eosinophilic inflammation affects the homeostasis of adenotonsillar [15,16]. LAR is known as a localized nasal allergic response without systemic atopy.…”

Section: Discussionmentioning

confidence: 99%

“…After exposure to aeroallergens, nasal Th2 IgE-mediated inflammation occurs in the tissue. Eosinophil cationic protein, eosinophils, mast cells, basophils, CD3 + T cells, and CD4 + T cells increase in the tissue [16]. LAR can be identified with multiple nasal provocation tests, locally produced specific IgE, or other local inflammation markers of allergic response.…”

Section: Discussionmentioning

confidence: 99%

Relationship between tissue and serum eosinophilia in children undergoing adeno-tonsillectomy with allergic rhinitis

2019

Turk J Med Sci

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Background/aim: Previous reports suggested that allergic/eosinophilic inflammation affects the adenoid and tonsillar tissue. The aim of this study is to evaluate and compare the tissue and serum eosinophilia in children undergoing adenotonsillectomy with allergic rhinitis. Materials and methods: The clinical registers of 125 children undergoing adenoidectomy/tonsillectomy due to adenoid/tonsil hypertrophy were examined and reviewed retrospectively. Fifty-seven children with positive skin prick test and symptoms of allergic rhinitis were included in the study as the atopic group, whereas 68 children with no allergic symptoms and negative skin prick test were included as the nonatopic group. Consequently, the total immunoglobulin E level and the serum and tissue eosinophilia of the atopic and nonatopic groups were compared. Results: Serum eosinophilia in the atopic group was found to be significantly higher than in the nonatopic group (P = 0.045). A significantly higher eosinophil count was found in adenoid/tonsil tissue of the atopic group (P < 0.001, P = 0.023, respectively). However, no significant correlation between tissue and serum eosinophilia was found. Conclusion: The inconsistency between tissue and serum eosinophilia in atopic children would particularly indicate a role of local atopy in adenotonsillar hypertrophy. Further studies are needed to better understand the effect and usefulness of serum and tissue eosinophilia in children with allergic rhinitis.

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“…En los últimos años, la rinitis alérgica local se describe como un fenotipo de rinitis que se caracteriza por producción de IgE específica y mediadores inflamatorios en la mucosa nasal, ausencia de IgE específica en el suero, pruebas cutáneas negativas y respuesta positiva a la prueba de provocación de alérgenos nasales. 9,10 La guía ARIA se implementa en más de 70 países alrededor del mundo. Desde su primera publicación en 2001 a la fecha se han realizado numerosas revisiones y actualizaciones.…”

Section: Clasificaciónunclassified

Tratamiento de la rinitis alérgica en pediatría en Argentina. Documento de actualización

Vázquez¹,

Onetti²,

Parisi

et al. 2020

RAM

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La rinitis alérgica (RA) es la enfermedad alérgica más frecuente. La prevalencia en niños y adolescentes de Argentina oscila entre 22.3 y 34.9 %. Ante esto, integrantes de los comités científicos de pediatría y rinitis de la Asociación Argentina de Alergia e Inmunología Clínica (AAAeIC) revisaron evidencia científica para actualizar las normativas terapéuticas de esta patología en la población pediátrica. La clasificación y categorización de la RA se encuentra actualmente en plena revisión en todo el orbe. Es necesario realizar un diagnóstico diferencial con otras rinitis no alérgicas en los niños, y confirmar la RA con base en la historia clínica, el examen físico, la determinación de biomarcadores o pruebas cutáneas. El tratamiento no farmacológico incluye la educación y pautas de control ambiental para alérgenos como ácaros, hongos anemófilos, epitelio de animales y pólenes. Se propone un tratamiento farmacológico escalonado de acuerdo con el control de la enfermedad. Los antihistamínicos de segunda generación no sedativos son la primera línea de tratamiento. La asociación con descongestivos orales no se recomienda en menores de cuatro años. Los corticoides nasales inhalados son de primera elección en formas moderadas y graves. El presente documento alerta a los pediatras sobre la importancia del diagnóstico precoz, el uso racional del tratamiento farmacológico escalonado y la inmunoterapia específica en niños.

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Update on local allergic rhinitis

Cited by 21 publications

References 55 publications

Local specific Immunoglobulin E among patients with nonallergic rhinitis: a systematic review

Local specific Immunoglobulin E among patients with nonallergic rhinitis: a systematic review

Relationship between tissue and serum eosinophilia in children undergoing adeno-tonsillectomy with allergic rhinitis

Tratamiento de la rinitis alérgica en pediatría en Argentina. Documento de actualización

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