“…Histamine binding capacity is reduced in atopic patients or even lacking [4,6,7,10], Within 3-4 weeks, normalization of the serum histamine binding capacity be sides freedom of clinical symptoms in cases of allergic rhinitis and allergic asth ma bronchiale should be achieved by ad ministering a histamine-gamma-globulin compound (12 mg human-gamma-globuiin and 0.15 ug histaminum dihydrochloricum; Histaglobin, Histadestal®) -produ cing immediate and long-acting effect.…”