Unsuspected intramedullary spinal cord metastasis detected by FDG PET/CT

Sahel, Omar Ait; Bazine, Aziz; Oueriagli, Salah Nabih; Benameur, Yassir; Biyi, A.; Doudouh, A.

doi:10.4103/ijnm.ijnm_150_20

Cited by 2 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Metastases usually have a history of malignancy, presenting in multiple nodular lesions, which can be accompanied by vertebral and accessory bone destruction and perineural edema. Both pathologies exhibit an increased FDG uptake; however, intradural astrocytomas and schwannomas usually have a lower FDG uptake than lymphomas or metastases ( 14 , 15 ). False-positives of PET/CT imaging in intraspinal lesions are primarily due to tuberculosis, abscess, inflammatory demyelinating lesions ( 16 , 17 ), where FDG metabolism levels are generally increased.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…In patients diagnosed with benign astrocytoma or schwannoma by MRI, PET is also useful for follow-up. When the uptake of FDG increases, it may indicate a malignant transformation of the tumor (5,15). The application of PET/CT in intravertebral lesions is limited, possibly due to the slightly lower spatial resolution of PET, whereas, with the continuous improvement of resolution, PET/CT can now clearly confirm the location.…”

Section: Gold Standardmentioning

confidence: 99%

See 2 more Smart Citations

Diagnostic value of ¹⁸F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study

Zheng¹,

Wanjun²,

Wang

et al. 2021

Med Int

View full text Add to dashboard Cite

the aim of the present study was to investigate the value of the use of fluorine-18 ( 18 F)-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) vs. magnetic resonance imaging (MRI) for the diagnosis of and differentiation between benign and malignant lesions in the spinal canal. For this purpose, a retrospective analysis was performed on the use of MrI and 18 F-FDG PET/Ct from January, 2017 to December, 2020, and the final diagnosis was obtained by performing a post-operative pathological examination or following a tissue biopsy (gold standard). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of the two examination techniques were calculated and comparisons between them were made. The PET metabolic parameters, maximum standardized uptake value (SUVmax), peak standardized uptake value (SUVpeak), mean standardized uptake value (SUVmean), metabolic tumor volume (MTV) and total lesion glycolysis (TLG) in the benign and malignant groups were calculated and compared, and the corresponding ROC curves were plotted. A total of 58 patients were enrolled, including 30 patients with malignant and 28 with benign lesions. The specificity of MRI was significantly higher than that of PET/CT (P<0.05). The sensitivity and negative predictive value of PET/Ct were higher than those of MRI, although with no significant difference (P>0.05). The mean ± tandard deviation values of the PET metabolic param-

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Gold Standardmentioning

confidence: 99%

See 1 more Smart Citation

Diagnostic value of ¹⁸F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study

Zheng¹,

Wanjun²,

Wang

et al. 2021

Med Int

View full text Add to dashboard Cite

show abstract

“…Авторы рекомендуют этот метод для диагностики крупных очагов с выраженным перифокальным отеком или как альтернативу для людей с противопоказаниями к МРТ [27]. Таким образом, ПЭТ / КТ представляет собой метод ранней диагностики ИММ [28].…”

Section: диагностикаunclassified

Intramedullary spinal cord metastases: current state of the problem

Ovchinnikov

Зуев

2022

Nejrohirurgiâ (Mosk.)

View full text Add to dashboard Cite

Intramedullary metastases are a rather rare manifestation of the underlying cancer. Their presence indicates an unfavorable prognosis and leads to a noticeable decrease in the quality of life. The absence of pathognomonic symptoms prevents the rapid and accurate identification of this pathology, which leads to a late diagnosis. The main methods of treating spinal metastases include surgical treatment; radiation and chemotherapy; steroid therapy. Refining diagnostic algorithms and optimizing protocols for managing patients with intramedullary metastases can help play a role in improving overall prognosis and patient survival. The review covers the epidemiology, the mechanisms of metastasis, the clinical picture, modern methods of diagnosis and treatment of intramedullary metastases, as well as the outcomes of this pathology. The main methods of treatment of spinal metastases include surgical treatment; radiation and chemotherapy; steroid therapy.

show abstract

Unsuspected intramedullary spinal cord metastasis detected by FDG PET/CT

Cited by 2 publications

References 8 publications

Diagnostic value of ¹⁸F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study

Diagnostic value of ¹⁸F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study

Intramedullary spinal cord metastases: current state of the problem

Contact Info

Product

Resources

About

Unsuspected intramedullary spinal cord metastasis detected by FDG PET/CT

Cited by 2 publications

References 8 publications

Diagnostic value of 18F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study

Diagnostic value of 18F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study

Intramedullary spinal cord metastases: current state of the problem

Contact Info

Product

Resources

About

Diagnostic value of ¹⁸F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study

Diagnostic value of ¹⁸F‑FDG PET/CT and MRI for intraspinal lesions: A comparative study