Unsuspected breast carcinoma presenting as orbital complication of rhinosinusitis

Fyrmpas, Georgios; Televantou, Despoina; Papageorgiou, Vassilios P.; Nofal, Farhat; Constantinidis, J.

doi:10.1007/s00405-007-0540-5

Cited by 23 publications

(16 citation statements)

References 9 publications

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“…Metastases of breast carcinoma to paranasal sinus have been rarely reported . Although many authors have highlighted the significance of the vertebral venous plexus in breast carcinoma to the head and neck region, other authors showed that ethmoidal involvement by metastatic carcinoma might be due to direct transcribrosal spread of tumor from meningeal involvement…”

Section: Primary Tumor Sitesmentioning

confidence: 99%

Metastases to nasal cavity and paranasal sinuses

et al. 2016

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The sinonasal cavities are rare locations for metastases. Metastases to these locations are usually solitary and produce similar symptoms to those of a primary sinonasal tumor. Nasal obstruction and epistaxis are the most frequent symptoms. The maxillary sinus is most frequently involved. The most common primary tumor sites to spread to this region originate in the kidney, breast, thyroid, and prostate, although any malignancy could potentially lead to a metastasis to the paranasal sinuses. The patient's prognosis is usually poor because of the fact that the sinonasal metastasis is usually associated with widespread disseminated disease. In the majority of patients, palliative therapy is the only possible treatment option. Nevertheless, whenever possible, surgical excision either alone or combined with radiotherapy may be useful for palliation of symptoms and, rarely, to achieve prolonged survival. This review considers the most interesting cases reported in the literature that presents metastases to the sinonasal cavities. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1847-1854, 2016.

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Section: Primary Tumor Sitesmentioning

confidence: 99%

Metastases to nasal cavity and paranasal sinuses

et al. 2016

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“…Breast cancer metastases to the sino-nasal-orbital area is an infrequent occurrence; with only five reported cases in the English literature [5,1,4,6,2]. This is an unprecedented case of orbital apex syndrome from metastatic breast cancer.…”

Section: Resultsmentioning

confidence: 87%

Orbital Apex Syndrome as the Initial Presentation of Metastatic Breast Cancer

Loftus¹,

Tan²

2013

Journal of Case Reports in Medicine

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Breast cancer metastases to the paranasal sinuses are an infrequent occurrence, and diagnosis is often delayed due to misdiagnosis of headache or sinusitis. We present a case of a 49-year-old female with a history of breast cancer status post bilateral mastectomy whose metastatic breast cancer to the paranasal sinuses first manifested as orbital apex syndrome. In the clinical picture of sinusitis with orbital complications, awareness for metastatic disease in patients with a history of cancer should be maintained in the appropriate clinical setting. Physicians should be mindful of the possibility of this diagnosis as these patients are often initially evaluated for non-specific symptoms such as headache and congestion. This is an unprecedented case of metastatic breast cancer first presenting as orbital apex syndrome.

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“…All the patients in this study presented with nasal symptoms. In literature review, RCC accounts for most cases [6,7], while metastatic tumors from the breast [8,9], colon [10], stomach [11] and prostate [3,12] have also been reported. RCC has a rich vascular stroma.…”

Section: Discussionmentioning

confidence: 99%

“…The most common sites for secondary breast cancer metastases are the lungs, liver, ovaries and adrenal glands [8]. Metastases of the skull base with paranasal sinus involvement are also reported.…”

Section: Discussionmentioning

confidence: 99%

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Distant Metastases to Nasal Cavities and Paranasal Sinuses Case Series

Azarpira

Ashraf

Khademi

et al. 2011

Indian J Otolaryngol Head Neck Surg

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Metastatic tumors to the nasal cavity and paranasal sinuses are far less common than primary cancer in this location. Review of the 2004-2010 pathology records of patients with sinonasal malignancy, revealed three cases with distant metastases to this region from primary sites in kidney, prostate and breast. The clinical presentation, histopathological findings and clinical outcome is presented for each patient. Metastases to the nose and paranasal sinuses usually respond poorly to treatment and have a poor prognosis. This report highlights the importance of suspecting metastases in patients with a previous history of malignancy. Therefore, thorough history and clinical evaluation is mandatory in any known/treated case of cancer.

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Unsuspected breast carcinoma presenting as orbital complication of rhinosinusitis

Cited by 23 publications

References 9 publications

Metastases to nasal cavity and paranasal sinuses

Metastases to nasal cavity and paranasal sinuses

Orbital Apex Syndrome as the Initial Presentation of Metastatic Breast Cancer

Distant Metastases to Nasal Cavities and Paranasal Sinuses Case Series

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