Unrecognized leather sofa dermatitis complicating chronic plaque psoriasis

Soriano, Livia Francine; Buckley, D. A.

doi:10.1111/cod.13810

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…Methylisothiazolinone (MI) has been reported as the allergen responsible of ACD caused by leather-care products used by patients to clean their leather sofas. 11 More recently, OIT, another isothiazolinone derivative, has also been implicated in sofa dermatitis [12][13][14][15][16] notably caused by car seats. 16 The latter type of chair was responsible for ACD in two of our patients (patients 1 and 2).…”

Section: Discussionmentioning

confidence: 99%

Sofa dermatitis: Value of patch test with 2‐(thiocyanomethylthio)benzothiazole

Herman

Baeck

2023

Contact Dermatitis

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Background: In 2008, numerous cases of allergic contact dermatitis caused by leather chairs (sofa dermatitis) were reported, with dimethylfumarate being the culprit allergen.However, octylisothiazolinone, methylisothiazolinone and cobalt have also been associated with cases of sofa dermatitis. An antifungal agent, 2-(thiocyanomethylthio)benzothiazole (TCMTB), has also previously been described as a contact allergen in leather.Materials and Methods: Seven patients were referred to the Department of Dermatology of the Cliniques universitaires Saint-Luc, Brussels, Belgium with suspicion of allergic contact dermatitis caused by leather sofas. They were patch tested with the European Baseline Series, additional series (according to the patients' history and clinical aspect of the eruption), dimethylfumarate (4/7 patients) and with TCMTB.Results: All seven patients presented a positive reaction to TCMTB and only one presented a concomitant positive reaction to dimethylfumarate. All patients showed clinical improvement after avoiding contact with their leather sofa. Conclusion:2-(Thiocyanomethylthio)benzothiazole (TCMTB) is probably an underestimated allergen present in leather chairs (responsible for the so-called 'sofa dermatitis'), and more generally in leather objects. It is, therefore, important to test with TCMTB 0.1% petrolatum in case of contact dermatitis related with leather products.

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Section: Discussionmentioning

confidence: 99%

Sofa dermatitis: Value of patch test with 2‐(thiocyanomethylthio)benzothiazole

Herman

Baeck

2023

Contact Dermatitis

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“…Reports on cases of contact allergy to BIT, OIT, DCOIT, and causative exposures, including non‐occupational and occupational exposure, are listed in Table 2 35–54 . Various types of products and materials included biocidal products in industry, detergents, leather articles (furniture and shoes), oils, paint, plastic and rubber articles, printing ink, and textiles (e.g., clothing and bed sheets).…”

Section: Skin Sensitizationmentioning

confidence: 99%

Increasing non‐cosmetic exposure and sensitization to isothiazolinones require action for prevention: Review

Lidén,

White

2024

Contact Dermatitis

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Frequent use of methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and MI in cosmetic products has been the main cause of widespread sensitization and allergic contact dermatitis to these preservatives (biocides). Their use in non‐cosmetic products is also an important source of sensitization. Less is known about sensitization rates and use of benzisothiazolinone (BIT), octylisothiazolinone (OIT), and dichlorooctylisothiazolinone (DCOIT), which have never been permitted in cosmetic products in Europe. BIT and OIT have occasionally been routinely patch‐tested. These preservatives are often used together in chemical products and articles. In this study, we review the occurrence of contact allergy to MI, BIT, OIT, and DCOIT over time, based on concomitant patch testing in large studies, and case reports. We review EU legislations, and we discuss the role of industry, regulators, and dermatology in prevention of sensitization and protection of health. The frequency of contact allergy to MI, BIT, and OIT has increased. The frequency of contact allergy to DCOIT is not known because it has seldom been patch‐tested. Label information on isothiazolinones in chemical products and articles, irrespective of concentration, is required for assessment of relevance, information to patients, and avoidance of exposure and allergic contact dermatitis.

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