This paper proposes dynamic and long-term negative bias temperature instability (NBTI) model for predicting circuit degradation. The real-time dynamic simulation is carried out by implementing the NBTI model into the compact MOSFET model HiSIM. Since this simulation approach is time consuming, a long-term model is developed, which enables to predict the device degradation after 10 years' usage. The aged device characteristics are able to be directly calculated from determined operation time, frequency and duty cycle.