United Arab Emirates National Newborn Screening Programme:an evaluation 1998-2000

Abstract

To evaluate the United Arab Emirate National Newborn Screening Programme we compared coverage, timeliness of programme indicators [age at sampling, recall and treatment initiation, timing of specimen delivery and laboratory results] and specimen quality with international st and ards. Recall rate, sensitivity, specificity, positive predictive values and relative incidence rates for phenylketonuria [PKU] and congenital hypothyroidism [CH] were calculated. Investigations for hypothyroidism included thyroid function studies [T3, T4, fT4 and TSH], technetium-99m thyroid scan when possible and thyroglobulin and thyroid antibodies when indicated. PKU investigations included plasma amino acids and measurement of biopterin defects. In the 6 years before December 2000, 138, 718 neonates were screened. Relative incidences for CH and for classic PKU were 1: 1570 and 1: 20, 050 respectively

Методы Диагностики Фенилкетонурии У Новорожденных

“…(0,0167%) [4], а самая низкая -в ОАЭ в 2003 г. (0,005%) [5]. Глобальное сравнение показателей заболеваемости между странами с общенациональными программами неонатального скрининга показывает, что в Японии среди азиатских стран наблюдается самый низкий уровень заболеваемости 1:125 000, тогда как заболеваемость в Китае составляет 1:17 000 [3].…”