Unit-of-Use Versus Traditional Bulk Packaging

So, Tiffany Y.; Wertheimer, Albert I.

doi:10.24926/iip.v3i1.251

Cited by 1 publication

(1 citation statement)

References 6 publications

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“…The unit-of-use packaging is not currently available in community pharmacies in Brazil. This type of commercial presentation of a drug product would be safer and more efficient, reducing unnecessary costs, the risk for counterfeiting, and the occurrence of medication errors [ 15 ]. Thus, despite the low prescription rates for these drugs, those patients provided with drug boxes probably received an irrational prescription.…”

Section: Discussionmentioning

confidence: 99%

Anxiolytics, Sedatives, and Hypnotics Prescribed by Dentists in Brazil in 2010

Lino

Martins

Silva

et al. 2017

BioMed Research International

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Objective To describe dental prescriptions for anxiolytics, sedatives, and hypnotics for Brazilian outpatients in 2010. Methods A cross-sectional study was conducted using data on the use of anxiolytics, sedatives, and hypnotics from the Brazilian Health Surveillance Agency, Brazil, 2010. For each prescription, prescribed drugs and the prescribed amount were identified. Prescribed medications were classified according to Anatomical Therapeutic Chemical code. We calculated the number of Defined Daily Doses (DDD) for anxiolytics, sedatives, and hypnotics by code, their mean DDD, and DDD per inhabitant per year. Results There were 16,436 prescriptions dispensed, including anxiolytics, sedatives, and hypnotics. These prescriptions corresponded to 3,555,780.50 mg, distributed as 2,286,200.50 mg (64.30%) of anxiolytics and 1,269,580.00 mg (35.70%) of sedatives and hypnotics. This amount allowed treating approximately 474,106 individuals (number of DDD). The anxiolytics most frequently dispensed were bromazepam (25.30%), alprazolam (19.19%), and diazepam (15.60%). Sedatives and hypnotics mostly prescribed were zolpidem (9.55%), midazolam (6.99%), and flunitrazepam (2.14%). The per capita rates (100,000 inhabitants) of anxiolytics and sedatives/hypnotics were 6.83 and 1.78, respectively. Conclusions Benzodiazepines and derivatives were the most frequently prescribed drugs. There was a low rate of dental prescriptions for anxiolytics, sedatives, and hypnotics, although excessive doses were concentrated in the same prescription.

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Section: Discussionmentioning

confidence: 99%