Unilateral lichen planus: A rare case report

Abstract

Oral lichen planus (OLP) is a mucocutaneous disease with well-established clinical and histopathological features. It has a prevalence of approximately 1%. The etiopathogenesis is poorly understood. The annual malignant transformation is less than 0.5%. There are no effective means to either predict or to prevent such event. Clinically, OLP present as bilateral symmetrical lesion and hence lichen planus isolated to a single oral site other than the gingiva is very uncommon. On the other hand lichenoid reaction (LR) are the lesions which are similar clinically and histopathologically with OLP, but they are induced with some drug reaction and usually they do not show bilateral pattern like lichen planus. We reported a very uncommon case of unilateral lichen planus which was clinically diagnosed as LR, but in the absence of any cause-effective relationship biopsy was taken for histopathological examination Histopathologically, LR cannot be differentiated with OLP, so the final diagnosis was made on the immunohistochemical ground.

A rare unilateral widespread multiple forms of oral lichen planus: clinico-histopathologic evaluation and diagnostic considerations: A case Report

“…In contrast to cutaneous lichen planus, the oral form may persist for up to 25 years. (15) In our case no cutaneous lesions were evident on any other part of the body other than intraoral areas, this finding was coincide with many previous studies. The typical age of presentation is between 30 and 60 years, and it is more frequently seen in women.…”

“…(13) Intraoraly, buccal mucosa, tongue and gingiva are most commonly involved. (14) They are usually symmetrical and bilateral lesions or multiple lesions in the mouth, (15) while other areas like mucosa of the palate and floor of the mouth are rarely affected (16) . Mucosal lesions are classified into six clinical forms, described by Andreason: Reticular, papular, plaque (white forms), the reticular form occurs more frequently and is characterized by white lacy streaks known as Wickham's striae, which generally are surrounded by discrete erythematous borders.…”

Unilateral Lichen Planus: A Rare Case Report

“…2,3,5,6 Unilateral oral LP has also been decribed. 7 However, in our pa ent the lesions did not strictly confi ne to the Blaschko's lines.…”

Bioimpedance Detection of Oral Lichen Planus Used as Preneoplastic Model

“…OLP is a chronic inflammatory disease affecting the oral mucosa, with a prevalence of about 1-2% of the population 16 . The histological picture of OLP is characterized by a dense sub-epithelial lymphocytes infiltration, increased number of intraepithelial lymphocytes, and the degeneration of basal keratinocytes.…”