Unicystic ameloblastoma of the maxilla: A case report

Paikkatt, V J; Sechachalam, Sreedharan; Kannan, V P

doi:10.4103/0970-4388.33459

Cited by 24 publications

(14 citation statements)

References 8 publications

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“…The majority of tumors are located in the third molar region, and 50−80% of cases are associated with an impacted tooth [2]. The histopathological features vary, and each of the subtypes may exist alongside a flat, odontogenic epithelial lining closely resembling a jaw cyst [18]. …”

Section: Discussionmentioning

confidence: 99%

Role of Immunomarkers in the Clinicopathological Analysis of Unicystic Ameloblastoma

Sah

Menon²,

Kamath³

et al. 2013

Disease Markers

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Purpose. The clinical behavior of unicystic ameloblastoma varies according to its subtype. The assessment of its proliferative capacity, neovascularization, and invasiveness using relevant immunomarkers may aid in appropriate surgical therapeutic protocol. Methods. 18 cases of clinically and histologically confirmed unicystic ameloblastoma, categorized as luminal, intraluminal, or mural subtypes, were analyzed retrospectively. Immunomarkers such as Ki-67, CD34, MMP-2, and MMP-9 were studied to evaluate their behavior. Results. Labeling index of Ki-67 was 4.25% in the intraluminal subtype, compared with 2.14% in the luminal and 4.04% in the mural variant (P = 0.3). CD34 immunostaining was significantly higher in the mural variant (43 per high power field) than the other two subtypes (P = 0.04). MMP-2 and MMP-9 were strongly expressed in mural, moderately in intraluminal, and weakly to absent in luminal variant. Conclusions. High proliferative index, angiogenesis, and protease activity in the mural ameloblastoma, ascertained by the expression of these markers, confirm its aggressive phenotype. The intraluminal and luminal subtype exhibiting decreased expression are compatible with their indolent clinical behavior.

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Section: Discussionmentioning

confidence: 99%

Role of Immunomarkers in the Clinicopathological Analysis of Unicystic Ameloblastoma

Sah

Menon²,

Kamath³

et al. 2013

Disease Markers

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“…[2] The unicystic type of ameloblastoma is one of the least encountered variant of the ameloblastoma accounting for about 10-15% of all ameloblatomas. [4–6]…”

Section: Discussionmentioning

confidence: 99%

Unusual imaging appearance of unicystic ameloblastoma

Nadendla

2012

Contemp Clin Dent

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Unicystic ameloblastoma (UA) refers to those cystic lesions that show clinical, radiographic, or gross features of a mandibular cyst, but on histologic examination show a typical ameloblastous epithelium lining part of the cystic cavity, with or without luminal and/or mural tumor growth. It accounts for 5-15% of all intraosseous ameloblastomas. We report a case of UA in a 35-year-old female with an unusual large multilocular (tennis racket) appearance on the right body of mandible and illustrate the importance and complexity of differential diagnosis with a brief review of recent literature.

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“…[23] observed an ameloblastoma in the area of premaxilla in a young teenager. A provisional diagnosis of radicular cyst was made.…”

Section: Discussionmentioning

confidence: 99%

An unusual case of unicystic intramural ameloblastoma and review of the literature

Ricci

Mangano²,

Tonelli

et al. 2012

Contemp Clin Dent

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Ameloblastoma is the most common tumor of odontogenic origin. There are various types of this tumor and confusion still exists among the clinicians about the correct classification. Multicystic ameloblastoma is the most frequent subtype while unicystic ameloblastoma can be considered as a variant of the solid or multycistic. This subtype is considered as a less aggressive tumor with a variable recurrence rate. However, its frequency is often underestimated. The aim of this article is reviewing the recent literature about unicystic ameloblastoma using our unusual clinical case as a starting point to illustrate this discussion. A 30-year-old man who had been complaining of slight pain in the premolar and molar area of the left side of mandible had a check up at our department. X-rays revealed a unilocular radiotrasparency with radiopaque margins. The first histological diagnosis was an odontogenic cyst. Successive histological evaluations revealed that ameloblastic epithelial islands were present in lassus connective tissue. We think that our case report provides new insights into the approach to the ameloblastoma diagnosis. We agree with authors who have pointed out that a single small biopsy may often be inadequate for the correct diagnosis of amelobastoma. Moreover, in the light of our experience, it should be kept in mind that ameloblastomas may have sometimes unusual presentations and this fact should induce surgeons and pathologists to consider carefully each lesion.

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Unicystic ameloblastoma of the maxilla: A case report

Cited by 24 publications

References 8 publications

Role of Immunomarkers in the Clinicopathological Analysis of Unicystic Ameloblastoma

Role of Immunomarkers in the Clinicopathological Analysis of Unicystic Ameloblastoma

Unusual imaging appearance of unicystic ameloblastoma

An unusual case of unicystic intramural ameloblastoma and review of the literature

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