Unexpectedly Superhigh Toxicity of Superbase-Derived Deep Eutectic Solvents albeit High Efficiency for CO₂ Capture and Conversion

Abstract

Superbase-derived deep eutectic solvents (DESs) are considered as biodegradable, low toxic, and sustainable solvents for efficient capture and conversion of carbon dioxide. However, do superbase-derived DESs have low toxicity just as reported? Herein, contradictory to the conventional thought, we find that the toxicity of superbase-derived DESs is super high. The toxicity of superbase-derived DESs in this work could be ca. 266 times that of DESs previously reported. Moreover, toxicity could be tuned by changing hydrogen bond donors, hydrogen bond acceptors, and mole ratios. The results indicate that the types of hydrogen bond donors had a paramount effect on the toxicity of DESs, and increasing the molar ratio of higher toxic components will also increase the toxicity of DESs. This work will provide possible ways to reduce the toxicity of DESs for achieving sustainable and green capture and conversion of carbon dioxide.

Designing Low Toxic Deep Eutectic Solvents for the Green Recycle of Lithium‐Ion Batteries Cathodes

“…The results of toxicity assessment in the A549 cell model showed that the addition of green and low toxicity components could effectively reduce the cytotoxicity of the corresponding DESs (Figure 6b). [99] Another research of the team showed that, the toxicity could also be adjusted by the molar ratio of components (Figure 6d, 6e), [100] which demonstrated that strategies to reduce DESs toxicity could be explored in terms of the ratio between structural composition and components of DESs. According to the idea, the low-cost, efficient and recyclable DESs could be further designed.…”

Manganese-based nanomaterials promote synergistic photo-immunotherapy: green synthesis, underlying mechanisms, and multiple applications

“…46,47 Ionic liquids (ILs) and deep eutectic solvents (DESs) are considered as new green solvents for the synthesis of NPs, 48 which have the advantages of easy synthesis, high stability and excellent solubility. 49,50 First, ILs and DESs have been reported to adjust the morphology of MnO 2 as structure guiding agents. Guo et al induced the synthesis of homogeneous Mn nanofilms with highly porous structures by adjusting the microstructure of Mn nanosheets with DESs.…”

Evaluation of phytochemical composition and metabolite profiling of macroalgae Caulerpa taxifolia and C. peltata from the Banda Aceh coast, Indonesia

“…Analianasari et al (2022) stated that an IC50 value of less than 50 mg/L is classified as having strong antioxidant activity, 50-100 mg/L is moderate, 150-200 mg/L is weak, and more than 200 mg/L is very weak. A low IC50 value indicates a strong ability of the extract to act as a hydrogen atom donor (Cao et al 2023). The high scavenging ability is related to the hydroxyl groups in phenolic compounds (Zhang et al 2022).…”