“…Attached cells in turn form hyphae which penetrate tissue (3,10,12). Therefore, the adhesive properties of C. albicans play a role in pathogenesis, and many studies have documented adhesive differences between strains (9, 11,16,18,23). In addition, adhesive differences between the bud and hyphal forms of growth have been demonstrated (3, 14), and in at least one strain, WO-1, adhesive properties vary as a result of high-frequency phenotypic switching (13).…”