Une histoire de peau

Boudana, David; Wolber, Alexis; Coeugniet, E; Martinot-Duquennoy, V.; Pellerin, P.

doi:10.1016/j.anplas.2009.08.003

Cited by 4 publications

(1 citation statement)

References 12 publications

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“…She was HIV, HBV and HCV positive. Six years before her death, a Thiersch graft [10] was placed in the left inguinal area to treat an abscess. Two years later, she presented with a thrombosis of the right deep femoral vein and post thrombotic syndrome of the right leg.…”

Section: Clinical Historymentioning

confidence: 99%

Ruptured pseudo-aneurysm of a femoral artery in a drug abuser revealed by post-mortem CT angiography

et al. 2012

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A 35-year-old drug addict was found dead in a public toilet with a ruptured groin, which was later diagnosed to be a leaking pseudo-aneurysm. Investigation at the scene revealed impressive external hemorrhage related to a groin wound. Post-mortem computed tomography angiography demonstrated an aneurysm of the right femoral artery with leak of contrast liquid. Signs of blood loss were evident at autopsy, and histological examination revealed necrosis and rupture of the pseudo-aneurysm. Toxicological analyses were positive for methadone, cocaine, citalopram, and benzodiazepines. This is the first case report in the literature of a ruptured femoral pseudo-aneurysm with a post-mortem radiological diagnosis.

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Section: Clinical Historymentioning

confidence: 99%

Ruptured pseudo-aneurysm of a femoral artery in a drug abuser revealed by post-mortem CT angiography

et al. 2012

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Graft orientation influences meshing ratio

Čapek

Flynn

Molitor

et al. 2018

Burns

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The Use of Human Sweat Gland–Derived Stem Cells for Enhancing Vascularization during Dermal Regeneration

Danner

Kremer

Petschnik

et al. 2012

Journal of Investigative Dermatology

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Vascularization is a key process in tissue engineering and regeneration and represents one of the most important issues in the field of regenerative medicine. Thus, several strategies to improve vascularization are currently under clinical evaluation. In this study, stem cells derived from human sweat glands were isolated, characterized, seeded in collagen scaffolds, and engrafted in a mouse full skin defect model for dermal regeneration. Results showed that these cells exhibit high proliferation rates and express stem cell and differentiation markers. Moreover, cells responded to angiogenic environments by increasing their migration (P<0.001) and proliferation (P<0.05) capacity and forming capillary-like structures. After seeding in the scaffolds, cells distributed homogeneously, interacting directly with the scaffold, and released bioactive molecules involved in angiogenesis, immune response, and tissue remodeling. In vivo, scaffolds containing cells were used to induce dermal regeneration. Here we have found that the presence of the cells significantly improved vascularization (P<0.001). As autologous sweat gland-derived stem cells are easy to obtain, exhibit a good proliferation capacity, and improve vascularization during dermal regeneration, we suggest that the combined use of sweat gland-derived stem cells and scaffolds for dermal regeneration might improve dermal regeneration in future clinical settings.

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Une histoire de peau

Cited by 4 publications

References 12 publications

Ruptured pseudo-aneurysm of a femoral artery in a drug abuser revealed by post-mortem CT angiography

Ruptured pseudo-aneurysm of a femoral artery in a drug abuser revealed by post-mortem CT angiography

Graft orientation influences meshing ratio

The Use of Human Sweat Gland–Derived Stem Cells for Enhancing Vascularization during Dermal Regeneration

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