Undifferentiated Sex Cord-Stromal Testis Tumor

Castelli, E.; Squeo, Maria Sara; Faraone, Nicola; Fiori, Cristian; Burlo, Paola; Fontana, Dario

doi:10.1097/01.ju.0000127748.49372.49

Cited by 3 publications

(7 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sex cord/gonadal stromal tumors (SCSTs) of the testis represent only 5% of all testicular neoplasms (1, 2), those with predominance of spindle cells in their morphology being difficult to classify. They have been reported under a variety of names (3): specialized gonadal stromal tumor (4), rete testis tumor (5), and testicular stromal tumor with myofilaments (6).…”

mentioning

confidence: 99%

Unclassified sex cord/gonadal stromal testis tumor with predominance of spindle cells

Tarján¹,

Sarkissov

Tot³

2006

APMIS

View full text Add to dashboard Cite

Unclassified sex cord/gonadal stromal tumors (SCSTs) of the testis comprised predominantly of spindle cells are extremely rare. It is important to differentiate these tumors from other testicular neoplasms, especially other types of sex cord/gonadal stromal tumors. In addition to histological criteria, immunohistochemistry plays an important role in the differential diagnosis. We describe a single case of this rare tumor type and discuss the differential diagnostics options based on a review of the related literature. The problem of the lack of reliable morphological prognostic factors is also addressed.

show abstract

mentioning

confidence: 99%

Unclassified sex cord/gonadal stromal testis tumor with predominance of spindle cells

Tarján¹,

Sarkissov

Tot³

2006

APMIS

View full text Add to dashboard Cite

show abstract

“…There were only three reported cases in the literature [2][3][4]. Table 1 summarized the clinical information and the management of the four cases, included our patient.…”

Section: Discussionmentioning

confidence: 89%

“…Objective tumor surveillance therefore relies on imaging study. Based on the evidence concluded from the reported cases [3,4], regular imaging surveillance for early detection of metastasis is recommended in the form of computer tomography of the thorax, abdomen and pelvis. Contrary to most neoplasm, recurrence of sex cord-stromal tumor is reported to occur up to 15 years after initial diagnosis [1].…”

Section: Discussionmentioning

confidence: 98%

“…The evidence to support prophylactic retroperitoneal lymphadenectomy for this rare tumor is also lacking. However, retroperitoneal lymphadenectomy may be the only effective treatment to stop disease progression in the presence of lymph node metastasis [4].…”

Section: Discussionmentioning

confidence: 99%

“…As for all other testicular tumors, radical orchidectomy is widely accepted as the primary treatment for undifferentiated sex cord-stromal tumor [2][3][4]. In the absence of overt metastasis at diagnosis, it is impossible to predict the malignant potential of this tumor, and this explains the importance of initial metastatic workup in defining the benign or malignant nature of such tumor [5].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Undifferentiated Sex Cord—Stromal Tumor in a Young Adult

Liu

Lai

et al. 2006

Int Urol Nephrol

View full text Add to dashboard Cite

Undifferentiated sex cord-stromal tumor in post-puberty male is extremely rare. There were only three reported cases in the literature. We reported a 19-year-old patient presented with an asymptomatic right testicular nodule with normal level of serum marker for germ cell tumor. Excisional biopsy and subsequent orchidectomy was preformed and the final pathology supported the diagnosis of undifferentiated sex cord-stromal tumor. He was then put on regular surveillance with no adjuvant therapy given. He remained disease free 18 months after the operation. A summary of the literatures and discussion on the management of this rare tumor was provided.

show abstract