Underweight is an important risk factor for coronary heart disease in the population of Ceningan Island, Bali

Abstract

A study on the prevalence of coronary heart disease (CHD) and its risk factors in Ceningan Island was conducted. The prevalence of CHD was 11.5%. Older age (odds ratio, OR, 27.0), underweight (OR, 3.6), systolic hypertension (OR, 4.6), high total cholesterol (OR, 5.9), and high low-density lipoprotein cholesterol (OR, 3.1) were risk factors for a history of myocardial infarction (MI). By logistic regression analysis, only age (B=3.937) and underweight (B=1.275) consistently appeared to be risk factors for MI. The prevalence of CHD in the population was comparatively high.

Homocysteine is related to peripheral arterial disease only in male elderly with type 2 diabetes mellitus

“…It may explain why no correlation between obesity and ABI was found. Reversed association concerning obesity and cardiovascular disease was shown in an epidemiological study in Nusa Ceningan by Suastika et al (2006), 26 in which the slim group had a greater prevalence of coronary heart disease as compared with that in those with greater body weight (normal to obese). It may be because of the fact that all of the samples were diabetics; glycemic control was not significantly related with ABI.…”

Association of Body Mass Index with Cardiovascular Disease Biomarkers

“…Underweight has been associated with coronary heart disease and myocardial infarction in a study in Bali, 3 and a pooled analysis on BMI in Asia 4 showed a lower odds of diabetes among underweight than normal-weight adults. By contrast, a study in Japan 2 reports a greater incidence of diabetes among underweight than normal weight older adults.…”

“…1 Less is known about underweight and morbidity, and results are equivocal. [2][3][4][5][6] These studies have been conducted in non-U.S.…”

“…Only a subsample of participants were assessed for fasting triglycerides, glucose, and LDL cholesterol. For fasting glucose, sample sizes for the 8 weight-status groups from underweight to obese class 3, respectively, was 51, 57, 51,3,262, 3,951, 2,263, 976, and 642. Sample sizes for fasting triglycerides were 45, 56, 50, 3,232, 3,927, 2,252, 970, and 632.…”

Age is an Important Risk Factor for Type 2 Diabetes Mellitus and Cardiovascular Diseases

“…The studies by Suastika et al in a remote area of Ceningan Island found that coronary heart disease (CHD) prevalence was relatively high (11.5%), and older age (male 45 years and female 55 years) had higher risk for CHD than younger age group (OR, 27.0). By logistic regression analysis of all variables of the risk factors, age ( =3.937) consistently appeared to be the risk factor for CHD (Suastika et al, 2012a). Age in the group with CHD (old myocardial infarction and myocardial ischemia) was significantly higher than those without CHD (65.0 vs. 58.5 vs. 40.5 years) (Suastika et al, 2012b).…”