Understanding the effects of Abhraka Bhasma on genotoxicity and its DNA repair potential in mouse model

Kulala, Divya S.; Prasad, T. S. Keshava; Reddy, Poojitha S.; Maruthiyodan, Swathi; Joshi, Manjunath B.; Satyamoorthy, Kapaettu; Guruprasad, Kanive Parashiva

doi:10.1016/j.jaim.2022.100598

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…The results have shown that there were no significant changes (p < 0.05) in the number of sperms and sperms with abnormalities when compared to control mice indicating that Abhraka Bhasma did not induce reproductive toxicity in mice. 21 Trivanga Bhasma: Thirty wistar strain male albino rats weighing 200±20g were selected and divided randomly into five groups, Group I was served as vehicle control group received honey as adjuvant. Group II was positive control group received distilled water (5ml/kg, po) with cyclophosphamide (40mg/kg, ip).…”

Section: Introductionmentioning

confidence: 99%

Safety of Ayurvedic Formulations at Genetic Levels Through Genotoxicity Studies

Ghetiya H.,

Patel U.,

Chaudhari S.

et al. 2023

IJIM

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Background: Ayurvedic formulations are routinely used in the therapeutics without any noticeable side effects. But doubts regarding their safety are always raised on scientific platforms. Considering this, there is need to evaluate safety of such Ayurvedic formulations containing heavy metals as an integral component. Materials and methods: Published research work on genotoxicity of Ayurvedic formulations have been screened and reviewed from different search engines and reputed databases in addition, dissertation works done at the Institute are also complied in the study. Results and conclusion: Results of Current research work has revealed that total nine safety studies have been published on genotoxicity of Ayurvedic formulations. In all the studies, formulations like Swarna Makshika Bhasma, Rasamanikya, Tamra Bhasma, Brahma Rasayana, Hridayarnava Rasa, Garbhapala Rasa, Abhraka Bhasma, Naga Bhasma, Trivanga Bhasma and Makaradhwaja were found to be safe when accessed for their genotoxic potential though containing heavy metals as an integral component

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Section: Introductionmentioning

confidence: 99%

Safety of Ayurvedic Formulations at Genetic Levels Through Genotoxicity Studies

Ghetiya H.,

Patel U.,

Chaudhari S.

et al. 2023

IJIM

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Modern Analytical Approaches in Bhasma Pariksha: Advancements and Challenges

Ranade

2023

J Ayurveda Homeopathy Allied Health Sci

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Bhasma Pariksha, an integral aspect of Ayurvedic medicine, involves assessing metallic and mineral-based formulations known as “Bhasmas” (herbomineral or herbometallic compounds). Traditional methods for evaluating Bhasmas have relied on visual, organoleptic, and Ayurvedic parameters. However, in recent years, the integration of modern analytical techniques has revolutionized the quality control and standardization of Bhasma formulations. This review aims to provide an in-depth overview of the rationale behind utilizing modern analytical methods for Bhasma Pariksha, highlighting the advantages and limitations of various techniques.

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Understanding the effects of Abhraka Bhasma on genotoxicity and its DNA repair potential in mouse model

Cited by 2 publications

References 37 publications

Safety of Ayurvedic Formulations at Genetic Levels Through Genotoxicity Studies

Safety of Ayurvedic Formulations at Genetic Levels Through Genotoxicity Studies

Modern Analytical Approaches in Bhasma Pariksha: Advancements and Challenges

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