Safety of Ayurvedic Formulations at Genetic Levels Through Genotoxicity Studies

Abstract

Background: Ayurvedic formulations are routinely used in the therapeutics without any noticeable side effects. But doubts regarding their safety are always raised on scientific platforms. Considering this, there is need to evaluate safety of such Ayurvedic formulations containing heavy metals as an integral component. Materials and methods: Published research work on genotoxicity of Ayurvedic formulations have been screened and reviewed from different search engines and reputed databases in addition, dissertation works done at the Institute are also complied in the study. Results and conclusion: Results of Current research work has revealed that total nine safety studies have been published on genotoxicity of Ayurvedic formulations. In all the studies, formulations like Swarna Makshika Bhasma, Rasamanikya, Tamra Bhasma, Brahma Rasayana, Hridayarnava Rasa, Garbhapala Rasa, Abhraka Bhasma, Naga Bhasma, Trivanga Bhasma and Makaradhwaja were found to be safe when accessed for their genotoxic potential though containing heavy metals as an integral component