Understanding Lymphatic Anatomy and Abnormalities at                     Imaging

Lee, Elizabeth M.; Biko, David M.; Sherk, William M.; Masch, William R.; Ladino-Torres, Maria; Agarwal, Prachi P.

doi:10.1148/rg.210104

Cited by 21 publications

(23 citation statements)

References 69 publications

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“…These lesions can be multifocal [ 2 ]. Central conducting lymphatic anomalies may also be associated with impaired flow and distension through central lymphatics [ 11 ]. Infectious etiologies including filariasis can also result in secondary lymphangiectasia and subsequent CC dilation [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“Mega” Cisterna Chyli: A Case Report and Review of the Literature

Chandra¹,

Murphy²,

Jordan³

et al. 2023

Cureus

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Enlarged cisterna chyli is an infrequently encountered entity and is most often an asymptomatic, incidental finding on imaging for other reasons. The pathogenesis of cisterna chyli enlargement is not well elucidated and includes infectious, inflammatory, and idiopathic causes. In this report, we present the rare case of an asymptomatic, markedly dilated "mega" cisterna chyli in a 60-year-old female.

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Section: Discussionmentioning

confidence: 99%

“Mega” Cisterna Chyli: A Case Report and Review of the Literature

Chandra¹,

Murphy²,

Jordan³

et al. 2023

Cureus

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“…This technique is often referred to as an interstitial injection. This approach has led to the development of innovative imaging techniques utilizing fluoroscopy such as intranodal lymphangiography, liver lymphangiography, mesenteric lymphangiography as well as dynamic contrast enhanced magnetic resonance lymphangiography and computed tomography lymphangiography ( Nadolski and Itkin, 2012 ; Chavhan et al, 2017 ; Lee et al, 2018 ; Itkin et al, 2020 ; Lee et al, 2022 ). These modalities allow for excellent visualization of most parts of the lymphatic system ( Figure 3 ).…”

Section: Lymphatic Anatomymentioning

confidence: 99%

Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium

Singhal

Börner²,

Chaikof³

et al. 2023

Front. Physiol.

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Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical scale is essential to discern how the structure and function of the lymphatic system interacts with different tissues and organs within the body and contributes to health and disease. The knowledge of molecular aspects of the lymphatic network is fundamental to understand the mechanisms of disease progression and prevention. Recent advances in mapping components of the lymphatic system using state of the art single cell technologies, the identification of novel biomarkers, new clinical imaging efforts, and computational tools which attempt to identify connections between these diverse technologies hold the potential to catalyze new strategies to address lymphatic diseases such as lymphedema and lipedema. This manuscript summarizes current knowledge of the lymphatic system and identifies prevailing challenges and opportunities to advance the field of lymphatic research as discussed by the experts in the workshop.

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“…Imaging-based evaluation of lymphedema is now used routinely for diagnostic confirmation and the evaluation of disease severity and distribution for treatment planning and response assessment. [23][24][25] Here, we will review the different ways by which MRI is used for the evaluation of lymphedema.…”

Section: Lymphatic Imagingmentioning

confidence: 99%

“…Noncontrast MRI provides static information and is thus unable to relay dynamic processes, for example active chyle leaks. 25 In moderate and severe cases of lymphedema, the lymphatic channels can be obscured by adjacent and overlying soft tissue edema. Lastly, the resolution of noncontrast sequences is generally lower than that of 3D gradient-echobased sequences used in contrast-enhanced studies.…”

Section: Mri Of Peripheral Lymphedemamentioning

confidence: 99%

MRI of Lymphedema

Salehi

Sibley

Friedman

et al. 2022

Magnetic Resonance Imaging

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Lymphedema is a devastating disease that has no cure. Management of lymphedema has evolved rapidly over the past two decades with the advent of surgeries that can ameliorate symptoms. MRI has played an increasingly important role in the diagnosis and evaluation of lymphedema, as it provides high spatial resolution of the distribution and severity of soft tissue edema, characterizes diseased lymphatic channels, and assesses secondary effects such as fat hypertrophy. Many different MR techniques have been developed for the evaluation of lymphedema, and the modality can be tailored to suit the needs of a lymphatic clinic. In this review article we provide an overview of lymphedema, current management options, and the current role of MRI in lymphedema diagnosis and management. Evidence Level 5 Technical Efficacy Stage 5

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Understanding Lymphatic Anatomy and Abnormalities at Imaging

Cited by 21 publications

References 69 publications

“Mega” Cisterna Chyli: A Case Report and Review of the Literature

“Mega” Cisterna Chyli: A Case Report and Review of the Literature

Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium

MRI of Lymphedema

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