Underserved Elderly Issues in the United States: Burdens of Oral and Medical Health Care

Greene, Veronica

doi:10.1016/j.cden.2004.11.001

Cited by 7 publications

(6 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Dental caries remains a major public health concern, despite widespread water fluoridation, education programs aimed at improving oral hygiene, and commercially available sugar substitutes (Marthaler, 2004). It is prevalent among families with low income and limited education (Tinanoff et al ., 2002; Greene, 2005) and in developing nations around the world (Smith, 2002; Marthaler, 2004). Streptococcus mutans has a clear association with the initiation and progression of dental caries, and efforts to curtail its pathogenic potential can improve oral health as well as general health throughout life (Allukian, 2000).…”

Section: Introductionmentioning

confidence: 99%

Gene Regulation in S. mutans

2011

View full text Add to dashboard Cite

Dental caries is a chronic infectious disease of multifactorial etiology that derives from the interplay among cariogenic bacteria on the dentition, the host diet, and other environmental exposures. Streptococcus mutans proliferates as a biofilm on the tooth surface, where it obtains nutrients and metabolizes fermentable dietary carbohydrates. The accumulation of lactic acid as a by-product of fermentation results in acidification of the plaque biofilm and demineralization of tooth enamel, marking the onset of decay. The ability of S. mutans to respond to environmental stresses presented by salivary flow, acid pH, oxidative stress, and changes in carbohydrate source and availability is essential for its survival and predominance in caries lesions. Importantly, S. mutans has evolved a network of regulators to integrate its cellular response to environmental change. Herein we describe the latest insights into global gene regulation in S. mutans, including mechanisms of signal transduction, carbon catabolite repression, and quorum-sensing. An improved understanding of these regulatory networks can provide a basis for novel therapeutic applications aimed at treating and/or preventing caries.

show abstract

Section: Introductionmentioning

confidence: 99%

Gene Regulation in S. mutans

2011

View full text Add to dashboard Cite

show abstract

“…There is also evidence that oral diseases impact cardiovascular, endocrine and pulmonary health particularly in the elderly, which will certainly provide additional stimuli for the elderly to seek dental care. [1] Therefore retention of teeth can have an impressive value on the overall dental, physical and mental health of an elderly individual. This review is based on a Pub Med data base search published in the period from 1990 to 2010 in various dental journals.…”

mentioning

confidence: 99%

Geriatric restorative care - the need, the demand and the challenges

Nadig¹,

Usha²,

Kumar³

et al. 2011

J Conserv Dent

View full text Add to dashboard Cite

Increased life expectancy is causing an explosion of the aging population that will continue now and in the foreseeable future. Improved quality of life at old age will demand tooth retention and consequently the need for restorative care. Retaining teeth disease free and maintaining them amidst multitude of risk factors associated with old age, is a multi- faceted challenge. This review article discusses the etiology of various dental diseases seen in older dentate population and their management keeping in mind the special needs of these matured people, so as to render a professional service that is sensitive and caring.

show abstract

“…Despite its decline over the last decades primarily due to the widespread use of fluoride compounds, caries disease activity in children is as high as 60–70% (Murata & Pardi, 2007; Taubman & Nash, 2006; García-Godoy & Hicks, 2008; Greene, 2005; Hausen, 1997; Peterson, 2003). Colonization of tooth surfaces by mutans streptococci and its interaction with constituents from the host’s diet is associated with the etiology and pathogenesis of dental caries in humans (Bowen, 2002; Marsh, 2003).…”

Section: Introductionmentioning

confidence: 99%

Effects of CO₂laser irradiation on matrix-rich biofilm development formation–an in vitro study

Zancopé

Dainezi

Nobre‐dos‐Santos

et al. 2016

PeerJ

View full text Add to dashboard Cite

BackgroundA carbon dioxide (CO2) laser has been used to morphologically and chemically modify the dental enamel surface as well as to make it more resistant to demineralization. Despite a variety of experiments demonstrating the inhibitory effect of a CO2 laser in reduce enamel demineralization, little is known about the effect of surface irradiated on bacterial growth. Thus, this in vitro study was preformed to evaluate the biofilm formation on enamel previously irradiated with a CO2 laser (λ = 10.6 µM).MethodsFor this in vitro study, 96 specimens of bovine enamel were employed, which were divided into two groups (n = 48): 1) Control-non-irradiated surface and 2) Irradiated enamel surface. Biofilms were grown on the enamel specimens by one, three and five days under intermittent cariogenic condition in the irradiated and non-irradiated surface. In each assessment time, the biofilm were evaluated by dry weigh, counting the number of viable colonies and, in fifth day, were evaluated by polysaccharides analysis, quantitative real time Polymerase Chain Reaction (PCR) as well as by contact angle. In addition, the morphology of biofilms was characterized by fluorescence microscopy and field emission scanning electron microscopy (FESEM). Initially, the assumptions of equal variances and normal distribution of errors were conferred and the results are analyzed statistically by t-test and Mann Whitney test.ResultsThe mean of log CFU/mL obtained for the one-day biofilm evaluation showed that there is statistical difference between the experimental groups. When biofilms were exposed to the CO2 laser, CFU/mL and CFU/dry weight in three day was reduced significantly compared with control group. The difference in the genes expression (Glucosyltransferases (gtfB) and Glucan-binding protein (gbpB)) and polysaccharides was not statically significant. Contact angle was increased relative to control when the surface was irradiated with the CO2 laser. Similar morphology was also visible with both treatments; however, the irradiated group revealed evidence of melting and fusion in the specimens.ConclusionIn conclusion, CO2 laser irradiation modifies the energy surface and disrupts the initial biofilm formation.

show abstract

Underserved Elderly Issues in the United States: Burdens of Oral and Medical Health Care

Cited by 7 publications

References 42 publications

Gene Regulation in S. mutans

Gene Regulation in S. mutans

Geriatric restorative care - the need, the demand and the challenges

Effects of CO₂laser irradiation on matrix-rich biofilm development formation–an in vitro study

Contact Info

Product

Resources

About

Underserved Elderly Issues in the United States: Burdens of Oral and Medical Health Care

Cited by 7 publications

References 42 publications

Gene Regulation in S. mutans

Gene Regulation in S. mutans

Geriatric restorative care - the need, the demand and the challenges

Effects of CO2laser irradiation on matrix-rich biofilm development formation–an in vitro study

Contact Info

Product

Resources

About

Effects of CO₂laser irradiation on matrix-rich biofilm development formation–an in vitro study