2015
DOI: 10.1016/j.healun.2014.11.023
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Uncorrected pre-operative mitral valve regurgitation is not associated with adverse outcomes after continuous-flow left ventricular assist device implantation

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Cited by 58 publications
(55 citation statements)
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“…Our mortality and morbidity was low, and in keeping with that of contemporary series of LVAD implantation. 9,15 We believe that certain aspects of our approach are key to safely performing mitral surgery at time of LVAD implantation. Avoiding aortic clamping may help preserve right ventricular function by reducing intraoperative ischemic injury.…”
Section: Discussionmentioning
confidence: 99%
“…Our mortality and morbidity was low, and in keeping with that of contemporary series of LVAD implantation. 9,15 We believe that certain aspects of our approach are key to safely performing mitral surgery at time of LVAD implantation. Avoiding aortic clamping may help preserve right ventricular function by reducing intraoperative ischemic injury.…”
Section: Discussionmentioning
confidence: 99%
“…Significant preoperative mitral regurgitation (MR) is thought to decrease after LVAD implantation and for this reason correction of MR is not indicated if ventricular recovery is not expected . Speed optimization—with the target mean arterial pressure 65–85 mm Hg, parallel positioning along the interventricular septum, intermittent opening of aortic valve, and less than moderate MR—should be done for appropriate ventricular unloading before discharge .…”
mentioning
confidence: 99%
“…Implantation of a LVAD leads to unloading of the LV, followed by a reduction in the LVEDV and mitral valve annular diameter, which would consequently result in a decrease in MR severity. Hence, a simultaneous mitral valve procedure is not recommended at the time of CF‐LVAD implantation . To our knowledge, only a few clinical studies regarding MR in patients receiving CF‐LVAD support have been conducted thus far.…”
Section: Discussionmentioning
confidence: 99%
“…Regurgitant flow is usually reduced under LVAD support, and volume unloading of the left ventricle (LV) leads to a reduction in mitral annular dilatation, followed by an improvement of MR. Although there is a general consensus that patients receiving CF‐LVAD do not require MR treatment at the time of LVAD implantation , the need for surgical repair in patients with severe MR or in patients receiving partial support is controversial. Excessive volume unloading of the LV can affect right ventricular (RV) function by causing a leftward shift of the interventricular septum (IVS; 3).…”
mentioning
confidence: 99%