Uncaria tomentosa (Willd. ex Schult.): Focus on Nutraceutical Aspects

Abstract

: Medicinal plants have been globally exploiting as an alternative to chemical drugs in the treatment of several diseases due to low unwanted side effects, environmentally friendly nature and low production costs, therefore, it is important to analyze the therapeutic properties of various medicinal plants to understand their potential bioactivity. Uncaria tomentosa is one of these medicinal plants with many health-promoting effects. Although the geographical resources of cat's claw go back to the remote tropics of the Amazon, industrialized countries use the plant extensively in trade. Various parts of the plants such as flowers, leaves, Stem, hook, and seed are mainly used medicinally to treat inflammation, asthma, allergies, skin impurities, microbial infections, neurodegenerative diseases, cancer, cirrhosis, gastrointestinal disorders, arthritis, heart disease, rheumatism, and fever. The end point of this review article is to prospectively scrutinize in vitro and in vivo the therapeutic potential of this plant, especially in terms of its nutritional applications and health beneficial effects.

The Role of Curcumin in Gastric Carcinoma by Modulating the Immune System and its SAR

“…This process involves a variety of immune cell types, particularly cytotoxic T cells 24 , natural killer cells 25 , and cytokines like tumour necrosis factor-α and chemokines 26 . According to reports from many parts of the world, medicinal herbs like Glycyrrhiza glabra 27 , Uncaria tomentosa 28 , Camellia sinensis 29 , Panax ginseng 30 , Prunus armenaica (apricot) 31 , Allium sativum 32 , Arctium lappa 33 , and Curcuma longa have a significant potential to treat cancer 34 . Fascinating research results have revealed that the primary components of these plants that are responsible for the anticancer effects are bioactive immunomodulators.…”