Un posible patrón de oro para el diagnóstico de loxoscelismo y una solución para la investigación

Pichardo-Rodriguez, Rafael

doi:10.4067/s0716-10182014000300018

Cited by 1 publication

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“…La araña es visualizada en aproximadamente 60% de los casos, pero correctamente identificada sólo en 13% 19 . Existen métodos en investigación en animales para la detección de la enzima esfinomielinasa D desde 30 min hasta cinco días tras ocurrir la mordedura 20 , pero que no son de uso habitual en la práctica clínica.…”

Section: Parasitologíaunclassified

Experiencia en loxoscelismo cutáneo y cutáneo visceral de manejo hospitalario: clínica, evolución y propuesta terapéutica

Puerto

Saldías-Fuentes²,

Curi

et al. 2018

Rev. chil. infectol.

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Experience in visceral cutaneous and cutaneous loxoscelism of hospital management: clinical, evolution and therapeutic proposal Background: Loxoscelism is a common pathology in our environment with a broad spectrum of differential diagnoses and presentations, with potentially serious complications, even to the point of death. To date, there is no standard treatment for these patients. Aim: To describe the clinical manifestations, main complications, therapeutic management, and evolution of loxoscelism in an inpatient setting from a tertiary hospital in Chile. Methods: All patients consulting and hospitalized in the hospital of the Pontificia Universidad Católica de Chile with diagnosis of loxoscelism between 2014 to 2017 and evaluated by dermatologist were included. Review of clinical files, including symptoms, images, laboratory parameters and treatment. Results: We evaluated seventeen inpatient with loxoscelism, whose presentation responds to the national epidemiological pattern. Most cases were managed with antibiotics, systemic corticosteroids, antihistamines, and dapsone. From these, 11.8% corresponded to viscerocutaneous loxoscelism, successfully managed with supportive measures, systemic corticosteroids and antihistamines. Fifty-nine percent healed their cutaneous lesions after one month of treatment, with slight residual scarring or post inflammatory hyperpigmentation, without associated mortality in our series. Discussion: Most cases of cutaneous loxoscelism presented excellent response and rapid resolution of the disease after combined therapy with systemic corticosteroids, antibiotics and dapsone, suggesting that the use of these therapies could stop the progression of cutaneous necrosis and prevent complications associated with loxoscelism.

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Section: Parasitologíaunclassified