Ultrastructural Examination of Failed Molar Retreatment with Secondary Apical Periodontitis: An Examination of Endodontic Biofilms in an Endodontic Retreatment Failure

Carr, Gary B.; Schwartz, Richard S.; Schaudinn, Christoph; Gorur, Amita; Costerton, J. William

doi:10.1016/j.joen.2009.05.035

Cited by 101 publications

(86 citation statements)

References 32 publications

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“…Proper removal of bacteria is crucial when performing root canal therapy. Bacteria may be located in areas distant from the main canal, including the lateral canals, an isthmus, or fins 3,12,16,17,19) . Such areas are physically impossible to reach with standard dental instruments, which makes mechanical cleaning and obtaining the required concentration for the cleaning agent difficult.…”

Section: Discussionmentioning

confidence: 99%

CBCT-based Diagnosis of Periapical Lesion of Maxillary First Premolar Mimicking That of Second Premolar

Fujii

Suehara

Sekiya

et al. 2016

Bull. Tokyo Dent. Coll.

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Apical periodontitis is usually diagnosed based on clinical findings and dental X-rays. Recently, however, dental cone beam computed tomography (CBCT), which provides 3-D images of the maxillofacial region, has enabled dentists to examine patients undergoing endodontic therapy more effectively, improving diagnostic accuracy. Here, we describe a positive treatment outcome achieved using CBCT to diagnose apical periodontitis of the maxillary premolars, which had proven difficult to diagnose based on clinical findings and dental radiography alone. The patient was a 42-year-old Japanese man who presented with the chief complaint of gingival swelling in the maxillary right premolar region. Our initial diagnosis, based on clinical findings and dental X-ray, was apical periodontitis of the maxillary right second premolar, and treatment was started. However, after the patient failed to respond to the treatment, CBCT was performed. Based on these new findings, the diagnosis was changed to one of apical periodontitis of the upper right first premolar, and the patient was treated accordingly. Previous studies have described the complex anatomical morphology of the upper premolars, noting multiple roots and variation in the morphology of the root canals. The 3-D images provided by dental CBCT allow better assessment of oral conditions than the traditional 2-D images provided by dental X-rays, which in turn enables the dentist to better select the most appropriate treatment. Here, the patient showed no symptoms and was progressing well at a 6-month follow-up visit. The present results indicate that when clinical findings and dental X-rays alone are insufficient to allow a secure diagnosis, CBCT offers an effective alternative which will enable the appropriate treatment to be selected more reliably.

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Section: Discussionmentioning

confidence: 99%

CBCT-based Diagnosis of Periapical Lesion of Maxillary First Premolar Mimicking That of Second Premolar

Fujii

Suehara

Sekiya

et al. 2016

Bull. Tokyo Dent. Coll.

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“…The presence of a complex, variable, multispecies biofi lm was recently demonstrated in the entire length of the isthmus of a tooth, which had initially been treated 10 years earlier and then retreated 2 years later [ 94 ]. Gram-positive and Gram-negative organisms were both detected.…”

Section: Models To Study Cleaning Of Isthmus Areasmentioning

confidence: 98%

Research on Irrigation: Methods and Models

Shen

Gao

Lin

et al. 2015

Endodontic Irrigation

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Irrigation is regarded by many as being the most important part of root canal treatment. It has several different functions and goals depending on the type of the irrigant used: irrigation reduces friction between the instrument and dentin, improves the cutting effectiveness of the fi les, and dissolves organic and inorganic matter. It also cools the tooth and the fi le; it has a washing effect and removes loose debris and bacteria from the canal. Last but not least, irrigation acts against root canal biofi lms. Irrigation is also the only way to impact those areas of the root canal wall not touched by mechanical instrumentation. The factors that remain a challenge in the irrigation and disinfection of the root canal include biofi lm resistance, poor penetration of the irrigant, and exchange of irrigants in the highly complex root canal anatomy. Progress in the search for better irrigants and irrigant delivery is necessary. A variety of different study models have been used in endodontic research on irrigation. One of the issues is how to make a rational choice for a study model that is relevant for the question at hand. This article presents an overview of the methods and models that have been used in endodontic literature to study irrigation.

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“…They also reported a positive relationship between the presence of biofilm and the radiographic size of the lesion. Other studies have reported the presence of biofilm at more diverse sites in root canals (76), in root canal ramifications and isthmuses (77), and on the exterior root surface (75). Their presence in teeth with persistent disease raised the question as to their possible role as an etiological factor in disease persistence.…”

Section: Biofilm In Endodonticsmentioning

confidence: 99%

Efficacy of Bacteriophage Treatment on Pseudomonas aeruginosa Biofilms

Phee

Bondy-Denomy

Kishen

et al. 2013

Journal of Endodontics

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Introduction: Bacterial viruses (phages) have been used successfully in the treatment of animal and human bacterial infections. This study examined the potential use of phage therapy against Pseudomonas aeruginosa strain PA14 biofilms in a root canal model. were treated with phages identified with potential biofilm-degrading activities. Posttreatment intra-canal samples using paper points and round burs were taken to assess phage and bacterial counts. Results: Part 1: We identified two phages (JBD4 and JBD44a) with putative biofilm degrading activities. Treatment of PA14 biofilms with these phages produced a significant reduction in the mean percentage of biomass in 24h (p<0.05) and 96h (p=0.08) biofilms. Part 2: In 24 and 96h PA14 biofilms in a root canal model, no significant difference was found in the number of colony forming units after phage treatment (p>0.05). Conclusion: Phage application significantly reduced the biomass of 24 and 96h PA14 biofilms grown on microplates, but did not produce significant reduction of 24 or 96h PA14 biofilms grown in the extracted tooth model.iii

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Ultrastructural Examination of Failed Molar Retreatment with Secondary Apical Periodontitis: An Examination of Endodontic Biofilms in an Endodontic Retreatment Failure

Cited by 101 publications

References 32 publications

CBCT-based Diagnosis of Periapical Lesion of Maxillary First Premolar Mimicking That of Second Premolar

CBCT-based Diagnosis of Periapical Lesion of Maxillary First Premolar Mimicking That of Second Premolar

Research on Irrigation: Methods and Models

Efficacy of Bacteriophage Treatment on Pseudomonas aeruginosa Biofilms

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