Ultrasound monitoring of temperature and coagulation change during tumor treatment with microwave ablation

Yang, Chunlan; Wu, Shuicai; Bai, Yanping; Gao, Hongjian

doi:10.1007/s11515-009-0022-9

Cited by 8 publications

(4 citation statements)

References 22 publications

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“…Thus, temperature distribution inside the tissue can be obtained by considering the dependence of T on the sound speed. Ultrasound-based thermometry emerged in 1979 [ 120 ] and then found broad acceptance in all HTs [ 121 , 122 , 123 , 124 ] except for HIFU ablation, where the employment of this method should be avoided to prevent cross-talking phenomena [ 125 ]. In addition to its non-invasiveness, this technique does not require ionizing radiation and is quite inexpensive as compared to other imaging techniques.…”

Section: Temperature Monitoring: Main Techniques and Applications In Bone Htsmentioning

confidence: 99%

Temperature Monitoring in Hyperthermia Treatments of Bone Tumors: State-of-the-Art and Future Challenges

Tommasi

Massaroni

Grasso

et al. 2021

Sensors

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Bone metastases and osteoid osteoma (OO) have a high incidence in patients facing primary lesions in many organs. Radiotherapy has long been the standard choice for these patients, performed as stand-alone or in conjunction with surgery. However, the needs of these patients have never been fully met, especially in the ones with low life expectancy, where treatments devoted to pain reduction are pivotal. New techniques as hyperthermia treatments (HTs) are emerging to reduce the associated pain of bone metastases and OO. Temperature monitoring during HTs may significantly improve the clinical outcomes since the amount of thermal injury depends on the tissue temperature and the exposure time. This is particularly relevant in bone tumors due to the adjacent vulnerable structures (e.g., spinal cord and nerve roots). In this Review, we focus on the potential of temperature monitoring on HT of bone cancer. Preclinical and clinical studies have been proposed and are underway to investigate the use of different thermometric techniques in this scenario. We review these studies, the principle of work of the thermometric techniques used in HTs, their strengths, weaknesses, and pitfalls, as well as the strategies and the potential of improving the HTs outcomes.

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Section: Temperature Monitoring: Main Techniques and Applications In Bone Htsmentioning

confidence: 99%

Temperature Monitoring in Hyperthermia Treatments of Bone Tumors: State-of-the-Art and Future Challenges

Tommasi

Massaroni

Grasso

et al. 2021

Sensors

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“…Some examples are focused ultrasound [4] and electromagnetic techniques [5]. These latter include two different modalities according to the operating frequency, which correspond to substantial different mechanisms of interaction between electromagnetic (EM) field and target tissues.…”

Section: Introductionmentioning

confidence: 99%

“…However, these have the drawback of being invasive and capable of providing only local information, so that the adoption of noninvasive monitoring techniques would be advisable. In particular, magnetic resonance [6] and ultrasound [4] imaging have been proposed in the literature (and tested in the clinics) to tackle this issue. However, besides electromagnetic compatibility issues, magnetic resonance involves high cost equipment with obvious drawbacks in terms of economic sustainability, whereas the actual effectiveness of ultrasounds when temperature increases is still an open issue, since transducers are blinded by a hyperechogenic cloud caused by water vaporization as temperature increases up to about 100 ∘ C. The above reported limitations of existing imaging modalities motivate the interest in alternative techniques, and a possible candidate in this respect is microwave tomography (MWT), which images the electromagnetic properties of the tissue using low-cost and portable equipment.…”

Section: Introductionmentioning

confidence: 99%

Exploiting Microwave Imaging Methods for Real-Time Monitoring of Thermal Ablation

Scapaticci

Bellizzi

Cavagnaro

et al. 2017

International Journal of Antennas and Propagation

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Microwave thermal ablation is a cancer treatment that exploits local heating caused by a microwave electromagnetic field to induce coagulative necrosis of tumor cells. Recently, such a technique has significantly progressed in the clinical practice. However, its effectiveness would dramatically improve if paired with a noninvasive system for the real-time monitoring of the evolving dimension and shape of the thermally ablated area. In this respect, microwave imaging can be a potential candidate to monitor the overall treatment evolution in a noninvasive way, as it takes direct advantage from the dependence of the electromagnetic properties of biological tissues from temperature. This paper explores such a possibility by presenting a proof of concept validation based on accurate simulated imaging experiments, run with respect to a scenario that mimics an ex vivo experimental setup. In particular, two model-based inversion algorithms are exploited to tackle the imaging task. These methods provide independent results in realtime and their integration improves the quality of the overall tracking of the variations occurring in the target and surrounding regions.

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“…The success of MWA depends in part on the ability to accurately monitor the evolution of the ablation zone during the therapy procedure. Magnetic resonance imaging (MRI) [4] and ultrasound imaging [5] have been explored as MWA monitoring modalities. However, MRI has several drawbacks in terms of cost and concerns about heating MR contrast agents [6].…”

Section: Introductionmentioning

confidence: 99%

TDOA-based microwave imaging algorithm for real-time microwave ablation monitoring

Kidera

Neira

Veen

et al. 2017

Int. J. Microw. Wireless Technol.

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Microwave ablation is widely recognized as a promising minimally invasive tool for treating cancer. Real-time monitoring of the dimensions of the ablation zone is indispensable for ensuring an effective and safe treatment. In this paper, we propose a microwave imaging algorithm for monitoring the evolution of the ablation zone. Our proposed algorithm determines the boundary of the ablation zone by exploiting the time difference of arrival (TDOA) between signals received before and during the ablation at external antennas surrounding the tissue, using the interstitial ablation antenna as the transmitter. A significant advantage of this method is that it requires few assumptions about the dielectric properties of the propagation media. Also the simplicity of the signal processing, wherein the TDOA is determined from a cross-correlation calculation, allows real-time monitoring and provides robust performance in the presence of noise. We investigate the performance of this approach for the application of breast tumor ablation. We use simulated array measurements obtained from finite-difference time-domain simulations of magnetic resonance imaging-derived numerical breast phantoms. The results demonstrate that our proposed method offers the potential to achieve millimeter-order accuracy and real-time operation in estimating the boundary of the ablation zone in heterogeneous and dispersive breast tissue.

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Ultrasound monitoring of temperature and coagulation change during tumor treatment with microwave ablation

Cited by 8 publications

References 22 publications

Temperature Monitoring in Hyperthermia Treatments of Bone Tumors: State-of-the-Art and Future Challenges

Temperature Monitoring in Hyperthermia Treatments of Bone Tumors: State-of-the-Art and Future Challenges

Exploiting Microwave Imaging Methods for Real-Time Monitoring of Thermal Ablation

TDOA-based microwave imaging algorithm for real-time microwave ablation monitoring

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