Ultrasound mediated green synthesis of rhodanine derivatives: Synthesis, chemical behavior, and antibacterial activity

Arafa, Wael A. A.; Fareed, Mervat F.; Rabeh, Saleh A.; Shaker, Raafat M.

doi:10.1080/10426507.2016.1146276

Cited by 9 publications

(5 citation statements)

References 20 publications

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“…β‐Cyclodextrin supramolecule is an eco‐friendly catalyst and represents a convenient, green, and economical tool in the one‐pot synthesis of rhodanine scaffold . An ultrasound mediated green synthesis of various rhodanine derivatives in poly(ethylene glycol) has also been reported .…”

Section: Synthesis Of Thiazolidinonesmentioning

confidence: 99%

“…The presence of two ─OH groups (electron donating) on the phenyl ring, one of them being at the ortho position and the other at any other position on the ring, contributes to an increase in the antioxidant activity. Thirty 4-thiazolidinone derivatives (27) were synthesized and assessed for significant 1,1diphenyl-2-picrylhydrazyl radical scavenging activity, taking Vitamin E as the reference. 1,1-Diphenyl-2picrylhydrazyl has an odd electron and so has a strong absorption band at a wavelength of 517 nm.…”

Section: -Thiazolidinones As Type III Secretion System Inhibitormentioning

confidence: 99%

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Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

Nirwan

Chahal

Kakkar

2019

Journal of Heterocyclic Chem

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Thiazolidinone is a biologically important five‐membered heterocyclic ring having almost all types of biological activities. This review covers various types of thiazolidinones, such as 2‐thiazolidinones, 4‐thiazolidinones, 5‐thiazolidinones, 2‐thioxo‐4‐thiazolidinones, and thiazolidiene‐2,4‐dione. The literature related to the physical properties, chemical reactions, and synthesis for these derivatives has been included. Recent advances in the biological activities reported for 4‐thiazolidinone derivatives, such as peroxisome proliferator‐activated receptor γ binders, follicle‐stimulating hormone agonists, cystic fibrosis transmembrane conductance regulator inhibitors, and antioxidants, have been covered in this review. Thus, this study may help in further optimizing these thiazolidinone derivatives as more effective drug agents.

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Section: Synthesis Of Thiazolidinonesmentioning

confidence: 99%

Section: -Thiazolidinones As Type III Secretion System Inhibitormentioning

confidence: 99%

Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

Nirwan

Chahal

Kakkar

2019

Journal of Heterocyclic Chem

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“…[26][27][28][29] Ultrasonic irradiation, compared with other conventional techniques, has some inherent merits, e.g., milder reaction conditions, higher yields, shorter reaction times and simpler work-ups. As part of our efforts to prepare bis-heterocyclic systems using environmentally-benign conditions, [30][31][32][33][34] we describe, herein, efficient protocols for the preparation of bis-oxazolones and bis-imidazoles driven by ultrasonic irradiation.…”

Section: Introductionmentioning

confidence: 99%

An eco-compatible access to diversified bisoxazolone and bisimidazole derivatives

Arafa¹,

Abdel‐Magied²

2018

Arkivoc

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An efficient, straight-forward and eco-friendly synthetic strategy for the assembly of novel bisoxazolones via a four-component, sequential reaction of dialdehydes, glycine, benzoyl chloride and acetic anhydride, using ultrasound radiation, is described. Additionally, a diverse group of new bisimidazoles has been synthesized in good yields by the sonication of diamines and (Z)-4-arylidene-2-phenyloxazol-5(4H)-ones. These approaches have resulted in a number of successful routes for the facile synthesis of bis-oxazolone and bis-imidazole frameworks within minutes of irradiation. Excellent outcomes using these environmentally-friendly parameters make these synthetic schemes ideal, sustainable, green-chemistry procedures and provide simple access towards the preparation of bisheterocycles.

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“…Multicomponent processes are undoubtedly one of the most efficient approaches to forming several important motifs in modern organic synthesis and pharmaceutical synthesis [24][25][26]. For example, rhodanines have been successfully synthesized through multicomponent processes [27][28][29][30][31][32][33]. However, almost all known methods involving multicomponent reactions cannot achieve the synthesis of 5-unsubstituted rhodanines.…”

Section: Introductionmentioning

confidence: 99%