Ultrasound in Percutaneous Absorption

Low-frequency ultrasound for drug delivery in the gastrointestinal tract

“…It was this capacity for delivery of a broad range of molecules, which motivated further exploration of this technology for drug delivery to parts of the body other than the skin. The application of low-frequency US in the GI tract was initially proposed by Kost and Langer in the mid 1980s through their patent application focusing on buccal delivery [10]. However, until recently, there were few reports in the literature investigating this method.…”