“…60 Nevertheless, a risk/ benefit ratio should be evaluated in each situation, considering that thoracotomy is one of the most painful surgical access and that loco-regional techniques are effective in pain management, reducing opioid use and related adverse effects, such as respiratory depression, sedation, nausea, and vomiting. 64 In the authors' experience, applying the previously mentioned suggestions for regional analgesia, performing a minimally invasive peripheral technique, such as the erector spinae plane block, as part of multimodal pain management could be considered a safe and effective procedure for postoperative pain after lung surgery 65 and can be a viable choice also during the pandemic. Moreover, because severe acute postoperative pain represents the most important risk factor for chronic pain after thoracic surgery, with a worse quality of life, pain management after surgery should not be disregarded even during this current critical situation.…”