Ultrasound diagnosis of multicystic dysplastic kidney: Is a confirmatory nuclear medicine scan necessary?

Whittam, Benjamin; Calaway, Adam; Szymański, Konrad M.; Carroll, Aaron E.; Misseri, Rosalie; Kaefer, Martin; Rink, Richard C.; Karmazyn, Boaz; Cain, Mark P.

doi:10.1016/j.jpurol.2014.03.011

Cited by 27 publications

(20 citation statements)

References 11 publications

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“…Those authors held that high blood pressure was quite common in children with MCDK, and the high blood pressure could be mitigated (12). Their findings were consistent with those of other authors (13–15). Seeman et al identified dynamic blood pressure in 25 MCDK children and found that the blood pressure of 5 cases (20%) was above the 95th percentiles, and there were 2 cases that suffered from high blood pressure both during the day and night, while the other 3 cases suffered from high blood pressure solely during the night (16).…”

Section: Introductionsupporting

confidence: 94%

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Feng

Zhu

Sun

et al. 2016

Experimental and Therapeutic Medicine

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The aim of the study was to summarize the preliminary experience of minimally invasive open nephrectomy operation on children with multicystic dysplastic kidney (MCDK). A retrospective review was performed on the clinical materials of the 15 children that had accepted consecutive minimally invasive open nephrectomies during the previous 2 years. The enrolled children were diagnosed with unilateral MCDK under computed tomography, emission computerized tomography and ultrasound and no anomaly in the contralateral functioning kidney was found. Of the 15 children, 12 were boys and 3 were girls, with 5 cases on the right and 10 cases on the left. Operations were completed at the retroperitoneal space in order to open an incision on the waists and ribs of the children, the length of which ranged from 1.5 to 2.0 cm (average 1.7 cm). The age of the children at operation ranged from 3 months to 5.6 years old, with an average of 2.4 years old. Surgery lasted for 30–50 min, with an average of 34.6 min. The estimated blood loss of each child was <5 ml. After operation, prophylactic intravenous antibiotics were administered for 2–4 days to prevent infection. All of the operations proved very successful. Following surgery the children were hospitalized for 2–4 days for observation, with an average of 2.8 days. No complications occurred during the follow-up period. In conclusion, minimally invasive open nephrectomy is effective for children with MCDK. The procedure is superior with regard to operative time, cosmesis, and length of stay. It is a safe and effective treatment choice for patietns with MCDK and can be easily performed on children.

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Section: Introductionsupporting

confidence: 94%

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Feng

Zhu

Sun

et al. 2016

Experimental and Therapeutic Medicine

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“…Firstly, we assumed that postnatal imaging could be used as the gold standard for diagnosis of renal tract anomalies. Given the larger object of interest and clearer views postnatally, we believe that this is a reasonable assumption. Secondly, we had a loss‐to‐follow‐up rate of 23.8%, which may have biased the data reported.…”

Section: Discussionmentioning

confidence: 97%

Diagnostic accuracy of midtrimester antenatal ultrasound for multicystic dysplastic kidneys

Scala

McDonnell

Murphy

et al. 2017

Ultrasound in Obstet & Gyne

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“…Imaging examination plays an irreplaceable role during the follow-up of MCDK (22,23). Ultrasonographic screening is not only of great significance in defining the development of MCDK, but also can prevent complications from infection or malignancy, thus, improving the quality of life for children with MCDK (23,24). However, studies found that routine VCUG and renal nuclear medicine scans may not be warranted in children with MCDK without hydroureteronephrosis or signs and symptoms of urinary tract infections (9,25).…”

Section: Discussionmentioning

confidence: 99%

“Watch and Wait” Strategy for Multicystic Dysplastic Kidney (MCDK): Status Survey of Perceptions, Attitudes, and Treatment Selection in Chinese Pediatric Urologists and Pediatric Surgeons

2020

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To investigate the perceptions, attitudes, and treatment selection of Chinese pediatric urologists and pediatric surgeons regarding a "watch and wait" strategy for multicystic dysplastic kidney (MCDK). We used a cross-sectional survey in this study. We sent the questionnaire to pediatric urologists and pediatric surgeons to capture their views via the "Questionnaire Star" online survey platform between November and December 2019. The questionnaire contained the basic information and surgical experiences of the respondent, respondents' awareness regarding the counseling of prenatally-diagnosed MCDK and the treatment of MCDK, and respondents' knowledge regarding the imaging modalities, frequency, and duration of follow-up. Of the 200 questionnaires we sent, we received 151 responses. Of those 151 complete responses, most respondents were women (n = 104, 68.9%), pediatric urologists (n = 78, 51.6%), and practicing with at least 5 years of surgical experience (n = 112, 74.2%); 11.9% reported >20 years' experience. Eighty-two surgeons (54.3%) provided positive counseling for prenatally-diagnosed MCDK. Ninety-nine surgeons (65.6%) advocated conservative management for MCDK, and only 14.8% of respondents suggested limiting the use of radiographic evaluation for MCDK. Surgeons working in academic teaching facilities and those from East China were more likely to select a "watch and wait" strategy. Chinese pediatric urologists and pediatric surgeons have inadequate knowledge of the "watch and wait" strategy for MCDK. An expert consensus on the strategy of "watch and wait" for MCDK in China is urgently needed to promote the application of this non-surgical treatment mode in clinical practice. A larger sample size is required to fully identify the current opinion of Chinese pediatric urologists and pediatric surgeons regarding the management of MCDK.

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Ultrasound diagnosis of multicystic dysplastic kidney: Is a confirmatory nuclear medicine scan necessary?

Cited by 27 publications

References 11 publications

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Minimally invasive open nephrectomy on children with multicystic dysplastic kidney

Diagnostic accuracy of midtrimester antenatal ultrasound for multicystic dysplastic kidneys

“Watch and Wait” Strategy for Multicystic Dysplastic Kidney (MCDK): Status Survey of Perceptions, Attitudes, and Treatment Selection in Chinese Pediatric Urologists and Pediatric Surgeons

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