Ultrasound Assisted Dispersive Liquid–Liquid Microextraction Followed by Injector Port Silylation: A Novel Method for Rapid Determination of Quinine in Urine by GC–MS

Abstract

Ultrasound-assisted dispersive liquid-liquid microextraction is rapid, simple and consumes less reagent for the analysis of polar analytes such as quinine.

Imprinted nanospheres based on precipitation polymerization for the simultaneous extraction of six urinary benzene metabolites from urine followed by injector port silylation and gas chromatography-tandem mass spectrometric analysis

“…To aovid these limitations, Rasmussen has proposed injector port derivatization which takes place inside the injector port of GC or GC-MS [35]. This will reduces the time required for derivatization (30 min to 1-2 sec) and amount of silylating reagent (100 µL to 1-2 µL) and also eliminates the requirement of external anhydrous conditions for silylation [36][37][38][39].…”

Simple and rapid analysis of acetaminophen in human autopsy samples by vortex‐assisted dispersive liquid–liquid microextraction‐thin layer chromatography‐image analysis

“…DLLME has been widely applied in the field of forensic toxicology for the determination of pesticide and their metabolites, drugs of abuse, benzodiazepines, narcotics and psychotropic substances, cannabinoids, toxic alkaloids, butylin compounds, over‐the‐counter drug, etc. [13,16,20–27].…”

Dispersion‐assisted quick and simultaneous extraction of 30 pesticides from alcoholic and non‐alcoholic drinks with the aid of experimental design

“…However, these traditional methods have limitations such as the use of large amount of toxic solvents, prolonged and expensive process. SPE has few advantages over LLE as it requires less amount of solvent in comparison to LLE, but the cartridges of SPE are very expensive . SPME is a modern technique which is widely used in microextraction for the analysis of the pesticides.…”