Ultrasound assessment of maternal adipose tissue during 1st trimester screening for aneuploidies and risk of developing gestational diabetes

Abstract

Introduction:The objective of the present study is to compare the sonographic measurement of subcutaneous adipose thickness and visceral adipose thickness during 1st trimester screening for aneuploidies between non-diabetic pregnant women and patients who develop 1st trimester or 2nd trimester gestational diabetes mellitus (GDM). Material and methods:Adipose thickness was measured by transabdominal ultrasound imaging in pregnant women attending our clinic for screening for fetal aneuploidies between 11 and 13 weeks of gestation. During the 1st trimester all patients were evaluated for fasting glycemia in accordance with the International Association of Diabetes and Pregnancy Study Groups (IADPSG) recommendations. Patients with confirmed fasting glycemia (FPG) ≥92 mg/dL were diagnosed as 1st trimester GDM. Patients with FPG <92 mg/dL underwent a 75-g oral glucose tolerance test between 24 and 28 weeks. Results:The study population included 238 non-diabetic women, 29 women with

Efeito agudo do ultrassom focalizado na redução da gordura abdominal sobre a composição corporal, parâmetro metabólico e variáveis cardiovasculares e autonômicas

“…Esses efeitos são decorrentes da ação térmica e mecânica as quais induzem tanto a necrose seletiva, quanto o processo de lipólise dos adipócitos, e secundariamente do aumento do metabolismo local visando a reparação tecidual, todos esses processos são mediados pela ação adrenérgica, podendo atingir um aumento da ação do sistema nervoso autônomo simpático. (D'Ambrosi et al, 2020) Na busca do equilíbrio da oferta e demanda de glicose no organismo, a insulina atua tanto na captação periférica de glicose quanto nos tecidos musculares e adiposos, nestes, a insulina estimula a lipogênese no fígado e reduz a lipólise nos adipócitos. (Czech, 2020) por meio do tratamento do ultrassom focado de alta potência atingiu a apoptose e necrose dos adipócitos, fato que implicou no aumento da oferta de triglicerídeos, ácidos graxos e a glicose para a corrente sanguínea, assim acredita-se ter favorecido a predominância parassimpática e o aumento dos índices rMSSD, HF ms 2 e SD1, no período de recuperação da terapêutica e contribuindo também para o incremento dos valores da modulação global e nos valores de colesterol.…”

Management of gestational diabetes in women with a concurrent severe acute respiratory syndrome coronavirus 2 infection, experience of a single center in Northern Italy

“…We expect to increase our study sample in the following months and thus provide further results. The main strength of this study is that it was conducted in one of the six reference centres for the treatment of COVID-19 in women in Lombardy, the first region to be affected by the disease in Europe and one of the areas with the highest diffusion rate of infection [1][2][3][4][5][6][7][8][9][10].…”

“…Among women with high‐risk pregnancies, those with gestational diabetes (GD) represent one of the largest subgroups. 4 , 5 The prevalence of GD is estimated at around 18% of pregnancies. 4 …”

Epicardial adipose tissue thickness as a potential predictor of gestational diabetes mellitus: a prospective cohort study

“…To date, although many risk factors for GDM have been identified (e.g., maternal age, obesity, and lipid Clinicians usually use BMI, VAT, and subcutaneous adipose tissue (SAT), to assess obesity when trying to predict GDM. However, SAT is not a good predictor for GDM during the first trimester [17,18]; neither is BMI [4,5,19]. Over recent years, several studies have revealed that VAT could be a good predictor for GDM in the first and second trimesters [18,19].…”

“…However, SAT is not a good predictor for GDM during the first trimester [17,18]; neither is BMI [4,5,19]. Over recent years, several studies have revealed that VAT could be a good predictor for GDM in the first and second trimesters [18,19]. It remains unclear whether EAT, as a special type of VAT, exerts a similar performance when screening for GDM.…”