“…It has also the advantage of being rapid, non-invasive and fairly simple to target to the area(s) of maximum pain (Sidhu & Rich, 1999). The sensitivity of ultrasonography in diagnosing osteomyelitis in sickle cell disease has been reported to be as high as 74% (Rifai & Nyman, 1997;Sadat-Ali et al, 1998;William et al, 2000;Riebel et al, 2003). However, as with computer tomography (Stark et al, 1991), the main 'diagnostic' finding (subperiosteal fluid) is not specific and can also be present during vaso-occlusive crises, although greater fluid depths (>4 mm) are reported to be highly associated with a diagnosis of osteomyelitis (William et al, 2000).…”