Ultrasensitive Voltammetric Quantification of Antioxidant Capsaicin at Platform Polypyrrole/Bi₂O₃/Graphene Oxide in Surfactant Stabilized Media

Abstract

An ultrasensitive electrochemical sensor has been developed for the detection and quantification of capsaicin antioxidant in solubilized system based upon electrocatalytic properties of polymer nanocomposite (polypyrrole/Bismuth oxide/Graphene oxide) based sensor. The developed sensor was characterized by scanning electron microscopy (SEM), Energy dispersive X-ray and Electron impedence spectroscopy. This polypyrrole-bismuthoxide-grapheneoxide based sensor exhibited higher stability and excellent electrocatalytic activity toward oxidation of capsaicin in solubilized media. The developed sensor had a dynamic linearity range of 80 to 800 ng/mL with limit of detection (LOD) and limit of quantification (LOQ) of 18 ng/mL and 59 ng/mL respectively. Electrochemical behavior of capsaicin at the developed sensor was investigated by square wave voltammetry. One of the major focus of present research was finding out alternatives to the use of organic solvents with the aim of diverting research toward greener chemistry by using less hazardous solubilizing media.

Folding and Assembly of Vanilloid Receptor Secondary-Structure Peptide with Hexahistidine Linker at Nickel–Nitrilotriacetic Acid Monolayer for Capsaicin Recognition

“…However, such methods often require extensive labor and expensive instruments, and the experiments tend to be time-consuming. Several voltammetric techniques − and impedance analysis are also under review with regard to items such as cost, ease of use, and sensitivity. They rely on various advanced materialse.g., carbon nanotubes, boron-doped diamonds, nanoparticles, and graphenefor electrode surface modification.…”

TiO2/(1-butyl-3-methylimidazolium hexafluorophosphate) Based Sensor: A Strategy for the Detection of Cinnamaldehyde

“…With increase in pH of solution, the cathodic peak potential for cinnamaldehyde shifted toward more negative potentials demonstrating that protons are involved in the reduction of cinnamaldehyde. 44 A linear relationship was observed between peak potential (Ep) of cinnamaldehyde and pH, which can be expressed by Equation 2, Ep/V Ag/AgCl = −0.0449 pH − 0.8377, R 2 = 0.9861 [2] Effect of different solvent system.-The effect of different solvent systems on cinnamaldehyde reduction was studied by square wave voltammetry. To assess the effect of solvents on peak current of CNN, a comparative study was performed in methanol, ethanol and DMF.…”

Recent advances in applications of surfactant‐based voltammetric sensors

“…Modification of an electrode containing various organic or inorganic compounds is a promising method for the detection process (Suherman et al, 2017). Different composite materials such as polypyrrole/bismuth oxide/graphene oxide (Verma & Jain, 2017), graphene nanosheet (Liu et al, 2012), graphene oxide/k‐carrageenan/ l ‐cysteine nanocomposite (Priya et al, 2018), graphene supported Pt nanoparticles composite (Yu et al, 2015), Cu/graphene nanocomposite (Zhu et al, 2020), CNT/pencil graphite composite (Tigari & Manjunatha, 2020), epoxy graphite composite (Almeida et al, 2017), pyrolytic graphite/single‐walled carbon nanotube (SWCNT) (Goyal et al, 2010), zeolites/MWCNT (Azab et al, 2019), and ZnFe 2 O 4 /SWCNTs (Dong et al, 2017) have been applied successfully for analyte detection using voltammetry and surfactants. Furthermore, thiabendazole (TBZ) and carbendazim (CBZ) exhibited higher electrochemical signals with CTAB compared to the absence of CTAB (Dong et al, 2017).…”