Ultrasensitive photoelectrochemical immunoassay for prostate-specific antigen based on silver nanoparticle-triggered ion-exchange reaction with ZnO/CdS nanorods

Abstract

Prostate-specific antigen (PSA), a glycoprotein that is most likely to cause prostate cancer, has attracted widespread attention in recent years due to its increasing threat to people's life and health....

Paper test strip for silver ions detection in drinking water samples based on combined fluorometric and colorimetric methods

“…Owing to the extensive use of Ag metal and Ag-based compounds in industry and daily life, the discharge of silver ion (Ag + )-containing waste into the environment acutely pollutes water, soil, and food (Liu et al, 2022). Ag + -based ion-exchange reaction and Ag nanoparticles also cause a long-term continuous leaching of Ag + (Shoults- Wilson et al, 2011, Lin et al, 2016, Huang et al, 2020, Zhu et al, 2021. Ag + can accumulate in the human body because Ag + easily reacts with thiol, amino, and carboxyl groups of functional enzymes and forms Ag + -polynucleotide complexes with DNA (Choi et al, 2016), which severely disrupts biological systems (Gao et al, 2017).…”

Characterizing a Silver Nanoparticle-Based Electrochemical Biosensor for Shiga Toxin Detection

“…The main limitation of the system would likely be related to antibody binding efficiency . Also, the science/technology behind the attachment of antibodies to AgNP is improving rapidly. , This improvement is driven by developments involving gold nanoparticle (AuNP) modification with antibodies, − but AgNP modification uses similar chemistry as is applied to the AuNPs. ,, …”

“…35 Also, the science/technology behind the attachment of antibodies to AgNP is improving rapidly. 36,37 This improvement is driven by developments involving gold nanoparticle (AuNP) modification with antibodies, 38−40 but AgNP modification uses similar chemistry as is applied to the AuNPs. 41,42,43 Additionally, the advantages of using AgNP-based electrochemical biosensors, specifically over AuNP-based electrochemical biosensors, are described as follows.…”

DNA walker-amplified signal-on electrochemical aptasensors for prostate-specific antigen coupling with two hairpin DNA probe-based hybridization reaction

“…12 However, these methods usually involve multiple washings and multi-separation steps during the assay. 13,14 One disadvantage of using conventional methods is that they easily cause systematic errors. Meanwhile, aptamers can bind a wide variety of specific targets with affinities and specificities that rival antibodies.…”